西宁市2013-2014年手足口病病原学流行特征分析

Hand,foot and mouth disease etiological epidemiological characteristics analysis in Xining city during 2013-2014

目的分析2013-2014年西宁市手足口病的病原学流行特征,探讨病原变化对疫情的影响。方法选取2013-2014年西宁市手足口病诊疗定点医院诊断的典型手足口病临床病例,采取其发病1周内的咽拭子进行实验室检测,对检测结果进行流行病学分析。结果 2014年西宁市手足口病以Cox A16为主要流行病毒,而2013年则以EV 71为主,不同年份各病毒类型分布差异有统计学意义(χ2=259.66,P<0.01)。病毒类型职业分布2013年差异无统计学意义(χ2=5.36,P>0.01),2014年差异有统计学意义(χ2=10.73,P<0.01)。EV 71、Cox A16和其他肠道病毒在不同年份所占比例差异较大。结论西宁市手足口病病原以Cox A16和EV 71为主,流行特点呈现交替主导,不存在混合感染情况。

Objective To analyze the etiological characteristics of hand,foot and mouth disease（ HFMD） from2013 to 2014 in Xining,so as to understand the etiological influence to epidemics. Methods Nasopharyngeal swabs of the cases from sentinel hospitals,the dates onset of cases were asked to within a week. Results CoxA16 as the main pandemic virus in 2014,but it changed as EV71 in 2013. Different years for various types of virus distribution have statistical significance（ χ2= 259. 66,P 〈0. 01）. Virus type professional distribution has no statistically difference in 2013（ χ2= 5. 36,P 〉0. 01） but it has statistically difference in 2014（ χ2=10. 73,P 〈0. 01）. EV71, Cox A16 or other intestinal viruses dominated epidemics in different years. Conclusions The pathogen of HFMD is given priority to with Cox A16 and EV71. The pathogen of etiological characteristics is alternately dominant. There isn＇t mixed infection.