Generation of monoclonal antibodies against n-3 fatty acid desaturase

Generation of monoclonal antibodies against n-3 fatty acid desaturase

下载PDF

导出

摘要 Dear Editor： Omega-3 polyunsaturated fatty acids （n-3 PUFAs） are essential fatty acids for normal cellular functions and have been used for prevention and treatment of many diseases, including coronary heart disease, dia- betes, and cancers. n-3 PUFAs and n-6 PUFAs have been shown to decrease and increase the severity of several human diseases, respectively. Unfortunately, Dear Editor： Omega-3 polyunsaturated fatty acids （n-3 PUFAs） are essential fatty acids for normal cellular functions and have been used for prevention and treatment of many diseases, including coronary heart disease, dia- betes, and cancers. n-3 PUFAs and n-6 PUFAs have been shown to decrease and increase the severity of several human diseases, respectively. Unfortunately,

作者 Yanfei Zhang Yilin Yuan Meilei Sheng Wei Zhang Ying Wang Xiao Zhang Yifan Dai

机构地区 Department of Genetics Jiangsu Key Laboratory of Xenotransplantation Department of Patholgy Key Laboratory of Antibody Technique

出处《The Journal of Biomedical Research》 CAS CSCD 2015年第6期515-517,共3页 生物医学研究杂志（英文版）

关键词 N-3脂肪酸单克隆抗体 N-3多不饱和脂肪酸 Ω-3多不饱和脂肪酸 n-6多不饱和脂肪酸脱氢酶必需脂肪酸严重程度

分类号 R392 [医药卫生—免疫学]

引文网络
相关文献

参考文献8

1Calder PC, Yaqoob P. Marine omega-3 fatty acids and coronary heart disease[J]. Curr Opin Cardiol, 2012,27(4): 412-419.
2Jafari T, Fallah AA, Azadbakht L. Role of dietary n-3 polyunsaturated fatty acids in type 2 diabetes: a review of epidemiological and clinical studies[J]. Maturitas, 2013,74(4):303-308.
3Chung H, Lee YS, Mayoral R, et al. Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer[J]. Oncogene, 2014,1-10.
4Wood KE, Lau A, Mantzioris E, et al. A low omega- 6 polyunsaturated fatty acid (n-6 PUFA) diet in- creases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans[J]. Prostaglandins Leukot Essent Fatty Acids, 2014,90(4):133-138.
5Kang ZB, Ge Y, Chen Z, et al. Adenoviral gene transfer of Caenorhabditis elegans n-3 fatty acid desaturase optimizes fatty acid composition in mammalian cells[J], Proc Natl Acad Sci U S A, 2001,98(7):4050-4054.
6Kang JX. A transgenic mouse model for gene-nutrient interactions[J]. J Nutrigenet Nutrigenomics, 2008, 1(4):172-177.
7Lai L, Kang JX, Li R, et al. Generation of cloned transgenic pigs rich in omega-3 fatty acids[J]. Nat Biotechnol, 2006,24(4):435-436.
8Wu X, Ouyang H, Duan B, et al. Production of cloned trans- genic cow expressing omega-3 fatty acids[J]. Tran- sgenic Res, 2012,21(3):537-543.

1敖翔,冯光德,何健,杨玉峰,王瑛,刘芳.n-3脂肪酸对肉鸡生产性能、器官指数及腿肌脂肪酸含量的影响[J].饲料广角,2017,0(1):36-39. 被引量：2
2董翠莲.在肉鸡饲料中添加鱼油的应用研究[J].黑龙江畜牧兽医,2006(10):69-69. 被引量：3
3牛占宇,史晓雪,霍鲜鲜,许鹏飞,张三润,闫婉姝,张润厚.日粮中添加具有不同脂肪酸特征的油籽对育肥绵羊脂肪组织中脂肪酸组成的影响[J].饲料工业,2017,38(3):43-48.
4Zachut,M,姜雅慧（摘译）,臧长江（校）.围产期奶牛饲喂n-3脂肪酸对生产性能，血浆、脂肪组织和乳脂中脂肪酸成分的影响[J].中国畜牧兽医,2011,38(4):73-73.
5杨家威,孙龙生,王恒,叶金明,丛宁,王如愿.不同脂肪源对罗氏沼虾脂肪酸组成的影响[J].水产养殖,2013,34(4):8-13. 被引量：2
6王翠燕,赵风云,孙璐,车会莲.转N-3脂肪酸去饱和酶基因猪肉对SD大鼠的亚慢性毒性研究[J].农业生物技术学报,2013,21(12):1434-1447.
7张敬,隋茁,潘振亮.散养蛋鸡集蛋应做好的3方面工作[J].养殖技术顾问,2012(7):13-13.
8Shen,X,Z,姜雅慧.公牛饲喂n-3和n-6多不饱和脂肪酸日粮对瘤胃和十二指肠食糜中反式-C18:1和CLA含量的影响[J].中国畜牧兽医,2012,39(4):118-118.
9N. Mach M. Devant I. D i az M. Font-Furnols 高俊(译).通过营养调节增加青年荷斯坦公牛肉中n-3脂肪酸的含量[J].饲料与畜牧（新饲料）,2006(5):53-53.
10杨彩霞,计成,丁丽敏,戎易.n-3脂肪酸的代谢和日粮α-亚麻酸强化鸡蛋的研究[J].中国农业大学学报,2000,5(1):117-122. 被引量：8

The Journal of Biomedical Research

2015年第6期

浏览历史

内容加载中请稍等...

Generation of monoclonal antibodies against n-3 fatty acid desaturase

参考文献8

相关作者

相关机构

相关主题

浏览历史