从广州市散发性脑炎病人血清中查出雪鞋野兔病毒抗体升高

RISE OF ANTIBODY IN HUMAN SERA AGAINST SNOW SHOE HARE VIRUS IN SPORADIC CASES OF ENCEPHALITIS IN GUANGZHOU

近几年来夏季,在我国南方一些省市发现一些散发性病毒性脑炎病例,主要是儿童。他们的流行性乙型脑炎抗体阴性。病因不明。 为了研究本病的病因,于1983年4月至10月,我们在广州市儿童医院收集了34例散发性脑炎病人的双份血清,15例其它病种(如百日咳、心肌炎、钩端螺旋体脑炎。

34 pair sera of sporadic encephalitis were collected from Guangzhou children hospital in southern China and tested against 14 different arbovi-rusal antigen ( VEE, CHIK, ROSE RIVER, POWASSAN 'TEMBUSU, LAN-GET, KUNJIN, JE, DENGE, NEGISHI, LACROSS, CE, SHOW SHOE HARE )by HI test.9/34 sera were positive:5 of them have 4 fold antibody rise against SSH when compared with acute sera and convalescent sera.The titer of acute sera were lower than 1/10, whereas the average titer of convalescent sera was 1/356.4 SSH positive cases occurage in May and one in July. Another 4 cases were positive to Negishi virus.The possibility of SSH as a cause of sporadic encephalitis in Guangzhou was discussed.