经尿道前列腺等离子电切术对前列腺增生患者的疗效及安全性研究

Safety and efficacy of plasma kinetic resection during prostate operation on patients undergoing hyperplasia of prostate

目的研究经尿道前列腺等离子电切术（plasma kinetic resection of prostate,PKRP）对前列腺增生患者的疗效及安全性。方法选择2009年2月~2014年2月在我院接受治疗的前列腺增生患者500例实施研究。根据数字法随机分成观察组及对照组,观察组使用PKRP术式进行治疗,对照组使用经尿道前列腺电切术（Transurethral resection of prostate,TURP）术式进行治疗,对比两组手术相关指标,两组治疗前后的国际前列腺症状评分（International Prostate Symptom Score,IPSS）、生活质量评分（Quality of Life,QOL）、最大尿流率（Maximal urinary flow rate,Qmas）及剩余尿流量（Residual urine flow,Ru V）指标水平,两组患者术后并发症情况。结果观察组的术中出血量显著少于对照组,差异有统计学意义（P〈0.05）。两组治疗后的IPSS、QOL、Qmas及Ru V水平较治疗前均有显著改善,但观察组的QOL评分在术后显著低于对照组,差异有统计学意义（P〈0.05）。观察组的术后总并发症发生率为10.80%（27/250）,显著低于对照组的18.00%（45/250）,差异有统计学意义（P〈0.05）。结论 PKRP术式治疗前列腺增生,具有较好的疗效及安全性,值得临床推荐。

Objective To study the safety and efficacy of plasma kinetic resection during prostate （PKRP） operation on patients suffering from hyperplasia of prostate. Methods 500 cases illed with hyperplasia of prostate and treated in our hospital from February 2009 to February 2014 were collected. All cases were divided randomly into test group and control group, The patients in the test group were treated surgically with PKRP while the patients in the control group were treated with TURP, Then operation Indexes, the International Prostate Symptom Score （IPSS） before and after treatment, quality of life score （QOL）, maximal urinary flow rate （Qmas） and residual urine flow （RuV） level, the complications of two groups of patients after operation were all evaluated between two groups. Results The amount of bleeding during operation in test group was significantly less than that in the control group（P＆lt;0.05）. IPSS, QOL, Qmas and RuV levels between two groups were all significantly improved after treatment than that before treatment. But postoperative QOL score in the test group was significantly lower than that in the control group, the difference was statistically significant （P＆lt;0.05）. total complication rate in the test group after operation was 10.80% （27/250）, which was significantly lower than 18% （45/250） in the control group（P＆lt;0.05）. Conclusion The PKRP technique can be used to treat benign prostatic hyperplasia with good curative effects and safety, and it is worthy to recommend in clinic.