1,2,3-三氮唑基二向2,2',6,6"-三联吡啶配体的设计与合成

Design and Synthesis of Ditopic 2,2',6,6"-Terpyridyl Ligands Based on 1,2,3-Triazole

以5-氨基苯二甲酸为原料,经重氮化、叠氮取代、Click成环、水热脱羧合成4'-三氮唑基间苯二甲酸,再经酯化、还原、PCC氧化合成4'-三氮唑基间苯二甲醛,此间苯二甲醛在碱性条件与2-乙酰吡啶反应,首次成功地合成和分离出1,2,3-三氮唑基二向2',2,6,6"-三联吡啶配体,并用1HNMR和MAl DI-To F质谱等对产物的结构进行了表征.

A novel terpyridine ligand was synthesized. 5- Aminoisophthalic acid was selected as the starting material. 5-（4-Carboxyl-1H-1,2,3-triazol-1-yl） isophthalic acid was obtained through diazotization, replacing by azide, and then cyclization with propiolic acid. 5-（4-Carboxyl-1H-1,2,3-triazol-1-yl）isophthalic acid was decarboxylated under the hydro-thermal condition. The intermediate product（di-aldehyde） has been synthesized through esterification, reduction, PCC oxidation. The di-aldehyde reacted with2-acetylpyridine to afford a novel ditopic 2,2＇,6,6＂-terpyridyl ligands based on 1,2,3-triazole. The correspondent products were characterized by1 HNMR and MALDI-To F Mass.