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强直性脊柱炎:一种被忽视的全身性疾病 被引量:3

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摘要 强直性脊柱炎(AS)是一种以中轴和外周关节炎症为主要临床表现的慢性自身免疫病与炎症性疾病,X线骶髂关节炎是诊断的主要标准之一,而肌腱附着点炎是AS的病理学特征。近年来国际风湿病学界对AS的认识发生了较大的改变,认为AS作为一种慢性系统性炎性疾病,除了侵犯中轴及外周关节外,还常伴随眼睛、皮肤、胃肠道、心血管等关节外器官的受累表现以及由此带来的焦虑、抑郁等各种心理症状,且眼睛、心脏等重要器官受累及心理疾患将会导致工作能力的丧失及更高的致残率,同时也会影响医生的治疗决策。2015年欧洲抗风湿病联盟大会上,许多学者提出应高度重视AS的关节外表现,并强调AS是一种全身性疾病这一观点,在制定治疗方案时需联合眼科、皮肤科、消化科甚至心理科等其他专科医师共同进行。
作者 李坤鹏 黄烽
出处 《浙江医学》 CAS 2015年第21期1727-1729,共3页 Zhejiang Medical Journal
基金 国家科技部"十二五"支撑计划(2014BAI07B05)
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参考文献15

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二级参考文献27

  • 1王莉莎,黄烽,张江林,张莉芸,邓小虎,张亚美,李晓峰,郭军华.肿瘤坏死因子拮抗剂治疗类风湿关节炎和强直性脊柱炎发生结核的风险[J].中华风湿病学杂志,2006,10(10):607-610. 被引量:18
  • 2朱剑,黄烽,张莉芸,张江林,张奉春,候勇,余德恩.寻找预测强直性脊柱炎患者接受3次infliximab治疗后10周病情改善及复发的指标[J].中华风湿病学杂志,2007,11(5):288-292. 被引量:9
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