CT在小儿神经母细胞瘤诊断和随访中的应用

Application of CT in diagnosis and follow- up of pediatric neuroblastoma

目的:评价CT检查在小儿神经母细胞瘤的诊断及治疗后随访中的临床应用价值。方法:回顾性分析23例经病理证实为神经母细胞瘤患儿的临床资料及CT表现特征。结果:23例神经母细胞瘤中来源于肾上腺13例,腹膜后7例,纵隔3例;15例肿瘤形态不规整,5例肿瘤呈椭圆形或类圆形,3例呈分叶状;肿瘤内部多呈混杂密度,20例瘤体内伴多发钙化灶,15例内伴囊性坏死低密度区,增强扫描后,17例瘤体呈明显强化,4例呈轻中度强化,2例未见明显强化;11例瘤体包绕大血管;CT正确诊断20例,诊断准确率为87.0%。结论:CT检查是诊断小儿神经母细胞瘤及治疗后随访观察的重要检查方法。

Objective： To evaluate the clinical value of CT in diagnosis and follow- up in pediatric neuroblastoma. Methods： The clinical data and CT features of 23 cases of neuroblastoma confirmed by pathology were analyzed retrospectively. Results： Among the 23 cases,13 cases were derived from adrenal gland,7 cases from retroperitoneal,3cases from mediastinum. The shapes of 15 tumors were irregular,those of 5 tumors were ellipse or similar to round,and those of 3 tumors were lobulated. The tumors mostly had mixed density,which with multiple calcification in 20 tumors and with cystidium and necrotic low density in 15. After contrast- enhanced CT scans,17 tumors had obvious enhancement,and 4 tumors had slight or moderate enhancement,and 2 tumors had no enhancement. 11 tumors wrapped around large vessels. CT diagnosed 20 cases accurately,and the correctly diagnostic rate was 87. 0%. Conclusion： CT was a very important check method for diagnosis and follow- up of pediatric neuroblastoma.