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miRNA在肿瘤放疗敏感性中的作用及机制 被引量：18

The functionand mechanism of miRNA in tumor radiosensitivity
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摘要 通过对近五年来关于miRNA与肿瘤放疗敏感性相关文献进行收集整理,从miRNA的结构功能、在电离辐射下反应的作用机制、与放疗敏感性之间的关系及miRNA在常见肿瘤(肺癌、食管癌、结直肠癌、乳腺癌及宫颈癌)中的作用等方面进行概述,并就microRNA的预后判断及放疗增敏作用等进行讨论。 To review the latest newly related literatures on radiotherapy miRNA and tumor sensitivity. We encapsulated the structure,function and the mechanism of miRNA under ionizing radiations. Also the relationship between miRNA and sensitivity to radiotherapy and the role of that in the treatment of common tumors（ such as lung cancer,esophageal cancer,colorectal cancer,breast cancer and cervical cancer）,were outlined. also the prognostic and irradiation enhancement effect of miRNA on human carcinoma cells.
作者 张玉虹 李皓 刘阳晨
机构地区 蚌埠医学院附属泰兴市人民医院
出处 《现代肿瘤医学》 CAS 2016年第2期314-318,共5页 Journal of Modern Oncology
关键词 肿瘤 MIRNA 放疗敏感性 tumor miRNA radiosensitivity
分类号 R730.55 [医药卫生—肿瘤]
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参考文献49

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二级参考文献42

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共引文献22

同被引文献149

引证文献18

二级引证文献55

现代肿瘤医学
2016年 第2期

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