孕期羊膜腔输注治疗羊水过少

Amniotic infusion for oligohydramnios

羊水过少可发生在妊娠的任何阶段,羊水指数≤3 cm与不良妊娠结局相关。羊膜腔输注是将生理盐水或乳酸林格氏液经腹或宫颈输入羊膜囊,纠正羊水过少。羊膜腔输注已经被证明是安全的,但仍需在充分评估羊膜腔输注的利弊后实施。羊膜腔输注目前主要应用在未足月胎膜早破的患者,可延长破膜至分娩的时间,预防肺发育不良和感染。但要推广羊膜腔输注作为临床的常规治疗手段,仍需更多的证据。

Oligohydramnios is characterized by a deficiency of amniotic fluid surrounding the fetus and can occur at any stage of pregnancy. Amniotic fluid index less than 3 cm is significantly associated with adverse pregnancy outcomes. Amniotic infusion is referred that instillation of saline or Ringer＇s lactate is instilled into the amniotic cavity through abdomen or cervix to correct oligohydramnios. Amniotic infusion is proved to be safe, but a complete evaluation of the benefits and complications of the operation is necessary before operation. Amniotie infusion is mainly applied in patients with preterm premature rupture of membranes, which can extend rupture-delivery time window and prevent risks of pulmonary hypoplasia and infection. However, more evidences are still required to promote amniotic infusion as a routine clinical treatment.