前降钙素和C反应蛋白对新生儿细菌感染的诊断价值分析

Value of procalcitonin and C-reactive protein in the diagnosis of neonatal bacterial infection

目的分析前降钙素(PCT)和C反应蛋白(CRP)对新生儿细菌感染的诊断价值。方法选择2013年1月-2014年12月我院收治的40例受到细菌感染的新生儿设定为感染组,选择同期出生的正常新生儿40例设定为正常组,比较两组新生儿血清前降钙素与C反应蛋白水平。结果正常组新生儿前降钙素为(1.6±0.06)μg/m L,C反应蛋白为(1.0±0.3)mg/L;感染组新生儿前降钙素为(31.3±21.1)μg/m L,C反应蛋白为(46.2±24.8)mg/L;感染组PCT和CRP明显高于正常组,对比差异显著(P<0.05)。结论分析前降钙素和C反应蛋白可以检测出新生儿的细菌感染情况,作为检测的重要指标及早为新生儿开展治疗具有重要诊断价值,值得推广应用。

【Objective】To analyze the procalcitonin（PCT） and C reactive protein（CRP） in diagnosis of neonatal bacterial infection. 【Methods】from 2013 January to 2014 December in our hospital 40 cases of bacterial infection in the neonatal setting as the infection group, normal neonates born during the same period 40 cases were set as normal control group,compared two groups of neonatal serum procalcitonin and C reactive protein level. 【Results】normal neonatal procalcitonin is（1.6±0.06） g/m L,C reaction protein（1±0.3） mg/L; neonatal infection group of procalcitonin for（31.3±21.1） g/m L, C reaction protein（46.2±24.8） mg/L;PCT and CRP infection group was significantly higher than normal grouphad significant differences（P〈0.05）. 【Conclusion】the analysis ofprocalcitonin and C-reactive protein C can detect bacterial infection ofthe newborn, as an important index for early detection of neonataldevelopment has an important diagnostic value of treatment, it is worthy of popularization and application.