经皮椎体成形术治疗对多节段脊柱转移性肿瘤患者疼痛椎体高度及Cobb角的影响

Effect of percutaneous vertebroplasty on pain,bertebral height and Cobb angle for patients with multi-segmental spinal metastatic tumor

目的探讨经皮椎体成形术治疗对多节段脊柱转移性肿瘤患者疼痛、椎体高度、Cobb角的影响。方法选取2009年1月至2014年9月间西安交通大学第二附属医院收治的28例多节段脊柱转移性肿瘤患者,给予经皮椎体成形术治疗,于术前、术后3d、6个月评估和比较患者疼痛程度、生活质量、椎体前缘、中央、后缘高度、Cobb角和术后并发症。结果与术前相比,术后3d、6个月患者视觉模拟疼痛评分及欧洲癌症治疗与研究组织评分均明显降低(均P<0.05);术后3d、6个月患者椎体前缘、中央、后缘高度均明显增高,Cobb角明显减少(P<0.05)。平均随访6个月,患者未出现骨水泥渗漏、血气胸等严重并发症。结论经皮椎体成形术治疗能够明显恢复多节段脊柱转移性肿瘤患者椎体高度及Cobb角,有效缓解疼痛,提高患者生活质量。

Objective To study the effect of percutaneous vertebroplasty on pain,bertebral height and Cobb angle for patients with multi-segmental spinal metastatic tumor. Methods From January 2009 to September 2014,the clinical data 28 patients with multi-segmental spinal metastatic tumor in The Second Affiliated Hospital of Xi＇an Jiaotong University treated by percutaneous vertebroplasty were retrospectively analyzed. On pre- and post-operative 3 days and 6 months,the pain degree,life quality,bertebral body fronterior / central / posterior heigh and Cobb angle,and the postoperative complications were evaluated and compared. Results Compared with the pre-operation,the Visual Analogue Scale（ VAS） scores and European Organization for Research and Treatment of Cancer（ EORTC） scores were significantly reduced on postoperative 3 days and 6 months（ P〈0. 05）; the bertebral body fronterior / central / posterior heigh were obviously increased and the Cobb angle was significantly decreased on post-operative 3 d and 6 mo（ P〈0. 05）.There were no severe postoperative complications such as bone cement leakage and hemopneumothorax on the average follow-up of 6 mo. Conclusions The percutaneous vertebroplasty can significantly restore the bertebral body heigh and Cobb angle for patients with multi-segmental spinal metastatic tumor and effectively relieve pain and improve the life quality. It is worthy of clinical promotion as the safe and effective operative treatment method.