2014年福建省第七次碘缺乏病病情监测报告

Report of the seventh time monitoring results of patients with iodine deficiency disorders in Fujian Province

目的了解福建省食用盐碘含量调整后人群碘营养水平和消除碘缺乏病进程。方法按人口比例概率抽样方法（PPS）在全省调查30个县（市、区）1507份居民户盐碘、1642名8～10岁儿童的甲状腺肿大率和甲状腺结节现患率、1619份儿童尿碘、623名孕妇尿碘。甲状腺检查采用B超法，盐碘测定采用直接滴定法（GB／T13025．7．1999），尿碘测定采用砷铈催化分光光度方法（WS／T107—2006）。结果食盐盐碘中位数为24．3mg／kg．合格碘盐食用率为92．0％（1387／1507）：8～10岁儿童甲状腺肿大率为3．1％（51／1642）、甲状腺结节现患率为14．4％（236／1642）；儿童尿碘中位数为154．3μg／L，其中〈50IXg／L的占7．5％（121／1619）；孕妇尿碘中位数为120．1μg／L，且63．7％（397／623）的孕妇尿碘〈150μg／L；30个监测点8～10岁儿童尿碘中位数与甲状腺结节现患率之间未见统计学相关性（r=0．043，P〉0．05）；按各监测点8～10岁儿童尿碘中位数分组（〈100、100。〈150、150～〈200、≥200μg／L），各组8～10岁儿童甲状腺结节现患率比较，差异无统计学意义[11.4％（17／149）、13．1％（60／457）、15．5％（141／910）、12．6％（13／103），x2=2．827，P〉0．05]。结论碘盐含量调整后，福建省各项指标保持“消除碘缺乏病”状态。食盐加碘含量已调整到位，一般人群碘营养水平处于适宜状态．不存在碘过量的问题。但在重点人群中，孕妇存在碘缺乏问题，8-10岁儿童甲状腺结节现患率与碘营养水平未见明显相关。

Objective To understand the iodine nutritional status of population and the progress of eliminating iodine deficiency disorders after the adjustment of iodine content of edible salt in Fujian Province. Methods Thirty counties were sampled by population proportion probability sampling in the whole province. The iodine level in edible salt from 1 507 households was tested by direct titration method （GB/T 13025.7-1999）; goiter rate and prevalence of thyroid nodules of 1 642 children aged 8 - 10 were examined by type-B ultrasound; urinary iodine level of 1 619 children and 623 pregnant women was determined by arsenic cerium catalytic spectrophotometric method （WS/T 107-2006）. Results The median of iodine level in edible salt from those 1 507 households was 24.3 mg/kg, the consumption rate of qualified iodized salt was 92.0% （1 387/1 507）; the goiter rate of those 1 642 children aged 8 - 10 was 3.1% （51/1 642）, their prevalence of thyroid nodules was 14.4% （236/1 642）, and the median urinary iodine level was 154.3 μg/L, among them, urinary iodine 〈 50 μg/L accounted for 7.5% （121/1 619）; the median urinary iodine level of pregnant women was 120.1 μg/L, and 63.7% （397/623） of them were less than 150 μg/[; the relationship between the median urinary iodine level and prevalence of thyroid nodules of those 1 642 children, was analyzed by the correlation test, r = 0.043, P 〉 0.05, those children aged 8 - 10 were divided into several groups base on the median urinary iodine level （ 〈 100, 100 - 〈 150, 150 - 〈 200, ≥200 μg/L）, among these groups, no significant difference of prevalence of thyroid nodules was observed [11.4% （17/149）, 13.1% （60/457）, 15.5% （141/910）, 12.6% （13/103）, X2 = 2.827, P 〉 0.05]. Conclusions All indicators have met the national standard of eliminating iodine deficiency disorders after the adjustment of iodine content of edible salt in Fujian Province. Iodine content of edible salt has been adjusted in place, in the general population, iodine nutritional level is in suitable condition. There exists no problem of iodine excess, but there is an iodine deficiency problem in pregnant women, among those children aged 8 - 10, the prevalence of thyroid nodules has nothing to do with the iodine nutritional level.