摘要
目的:了解我院药品不良反应(ADR)发生的特点及规律,促进临床合理用药。方法:回顾性分析2013-2014年我院上报国家ADR监测中心的317例ADR报告,对患者性别、年龄、给药途径、涉及的药品种类、ADR累及器官/系统及临床表现等进行统计、分析。结果:317例ADR中,发生人群女性比男性略多;41-70岁患者所占比例最高,达53.94%;由抗菌药物导致的ADR所占比例最高,为35.65%;静脉滴注给药引发的ADR占74.76%;ADR临床表现以皮肤及其附件损害最为常见,占30.28%。结论:ADR的发生与药品的性质、患者的个体差异、临床应用途径等多种因素相关,临床应严格掌握用药指征,加强ADR监测工作,促进临床安全合理用药。
OBJECTIVE:To probe into the characteristics and regularity of adverse drug reactions(ADR)reports in our hospital,and to promote rational use of drug. METHODS:In retrospective study,317 ADR cases reported by clinical departments of our hospital from 2013 to 2014 were analyzed statistically in respects of patient's gender,age,drug type,route of administration,organs or systems involved in ADR,clinical manifestation. RESULTS:Of 317 ADR cases,female who occurred were slightly more than male;the 41-70 year-old patients held the highest peroportion of 53.94%,35.65% were induced by anti-infective drugs,74.76% induced by intravenous dripping;30.28% manifested as lesion of skin and its appendants. CONCLUSIONS:ADR is associated with a variety of factors including drug property,individual differences and route of administration,etc. It is important to fo1 low indications in drug use and strengthen ADR monitoring to promote rational use of drugs.
出处
《中国药房》
CAS
北大核心
2015年第35期4957-4959,共3页
China Pharmacy
关键词
药品不良反应
合理用药
报告
分析
Adverse drug reaction
Rational use of drugs
Report
Analysis