十味柴黄合剂对女性肝郁血热型痤疮的临床研究

A Study of Ten Flavors of Chai Huang Mixture on Female Ganyu Blood Heat Type Acne

目的探讨十味柴黄合剂治疗女性肝郁血热型痤疮的临床效果。方法 140例女性肝郁血热型痤疮患者随机分为治疗组和对照组各70例,治疗组给予口服十味柴黄合剂治疗,对照组给予口服多西环素片联合外用0.1%阿达帕林凝胶治疗。结果治疗组在治疗4周及8周的有效率分别为41.4%及85.8%;对照组分别为34.3%及80.0%,治疗组有效率稍高于对照组,但无统计学意义(P>0.05)。结论十味柴黄合剂有效率与外用阿达帕林凝胶联合口服多西环素效果相当,不良反应小,有较好的临床应用价值。

Objective To study the therapeutic effect of the Ten flavor of Chai Huang mixture in the treatment of female Ganyu blood heat type acne.Methods 140 cases of female Ganyu blood heat type acne patients were randomly assigned into treatment group and control group,70 ca-ses in each group.The treatment group was treated with Ten flavor of Chai Huang mixture, while the control group was treated with doxycycline tablets combined with 0.1%adapalene gel.Results The effective rates of the treatment group after 4 weeks treatment and 8 weeks treatment were 41.4%and 85.8%;the effective rates of the control group were 34.3%and 80%. The effective rates of treatment group were slightly higher than those of control group.Thus there was no significant difference between the treatment group and the control group （ P〉0.05） .Conclusion The Ten flavor of Chai Huang Mixture has similar effect with the adapalene gel and doxycycline in the treatment of female Ganyu blood heat type acne,but it has fewer ad-verse reactions and high clinical value.