恶性梗阻性黄疸患者行PTCD和PTBS前后生活质量调查分析

Analysis of quality of life of patients with malignant obstructive jaundice before and after PTCD and PTBS

目的评价恶性梗阻性黄疸患者行PTCD和PTBS前后的生活质量。方法运用生存质量核心量表-30(QLQ-C30)及恶性梗阻性黄疸患者特异性条目池(QLQ-MOJ11),对92例恶性梗阻性黄疸患者,行PTCD和PTBS前后的生活质量进行调查。结果此类患者行PTCD和PTBS后生活质量得到了改善和提高,QLQ-C30分值测评,在功能领域得分:情绪功能、社会功能、总健康状况得分高于治疗前得分;单一条目得分:失眠、食欲丧失低于治疗前得分,分值差异具有统计学意义(P<0.05)。QLQ-MOJ11分值测评,症状领域3条目中,术后分值低于术前,手术前后分值差异具有统计学意义(P<0.05),黄疸、瘙痒和消化症状有明显缓解。结论恶性梗阻性黄疸患者行PTCD和PTBS能明显改善黄疸症状,可有效提高患者的生活质量。

Objective： Evaluation the quality of life of malignant obstructive jaundice patients before and after PTCD and PTBS. Methods： Using the survey of QLQ-C30 and QLQ-MOJ11,we investigated the quality of life of malignant obstructive jaundice patients before and after PTCD and PTBS. Results： Patients which operate on PTCD and PTBS have improved the quality of life. Evaluation of the score of QLQ-C30,In the field of function score： the score of emotional function,social function,total score is higher than previous score of before treatment; Single entry score： insomnia,loss of appetite scored lower than before treatment; In the field of single entry score： the score of insomnia,loss of appetite is lower than the previous score of before treatment,Score difference is statistically significant（ P〈0. 05）. Evaluation of the score of QLQ-MOJ11,in the field of symptoms domain entries： the score of postoperative lower than the preoperative,score differences between before and after operation are statistically significant（ P〈0. 05）,the symptoms of jaundice itching and digestive have significantly alleviated. Conclusion： Patients with malignant obstructive jaundice which operate on PTCD and PTBS can obviously improve the symptoms of jaundice and effectively improve the quality of life.