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血清AFP、TK1、DKK1联合检测对原发性肝癌的诊断价值 被引量:21

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摘要 目的探讨血清甲胎蛋白(AFP)、胸苷激酶1(TK1)、分泌型蛋白Dikkopf-1(DKK1)联合检测诊断原发性肝癌(PHC)的价值。方法选择84例PHC患者作为PHC组,50例良性肝病患者作为良性肝病组,50例健康体检者作为对照组,检测3组血清AFP、TK1、DKK1水平并进行组间比较。结果 PHC组血清AFP、TK1、DKK1水平均显著高于良性肝病组和对照组(P均<0.05);三项指标联合检测诊断PHC的灵敏度、特异度均显著高于各单项指标检测结果(P均<0.05)。结论血清AFP、TK1、DKK1联合检测诊断PHC的灵敏度、特异度均较高,对临床诊断PHC有重要的参考价值。
出处 《现代中西医结合杂志》 CAS 2016年第1期94-95,98,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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