颈动脉粥样硬化与管腔断面血流播散率研究

The study of carotid atherosclerosis and carotid artery turgor vitalis

目的探讨不同时期颈动脉粥样硬化患者颈动脉断面血流播散情况及分布特点。方法对133例动脉粥样硬化患者进行颈动脉内血流直径播散率测算.在以有无动脉粥样斑块分为动脉粥样硬化无斑块组(A组)60例动脉粥样硬化有斑块组(B组)73例,另设63例颈动脉内-中膜无增厚且无动脉粥样硬化斑块者为对照组(C组)。结果颈动脉内血流直径播散率对照组(29.83±7.587)%,硬化组(37.92±7.733)%,斑块组(47.08±9.613)%,三组组间两两比较存在差异,有统计学意义,对照组与硬化组比较存在差异(P<0.01),对照组与斑块组存在差异比较存在差异(P<0.01).硬化组与斑块组比较存在差异(P<0.01)。结论动脉粥样硬化不同时期,管腔边缘血流状态也随之发生相应改变,可以用血流播散率进行量化表示。此表现符合低壁切应力假说,为低壁切应力假说提供影像学依据。

Objective To explore the distribution of turgor vitalis in patients Carotid artery section, who suffered from carotid artery atherosclerosis in different periods. Methods For measuring the rate of turgor vitalis of carotid artery sec- tion in 133 cases with atherosclerosis, the 133 cases were divided into 60 cases （group A） without plaque and 73 cases （group B） with atherosclerotic plaques. And, at the same time, there were 63 cases as control group who had suffered from intimal thickening and Atherosclerotic plaques. Results The above experiment offered the rate of turgor vitalis. The rate of groupc is （29.83±7.58）%, the rate of group A is （37.92±7. 733）%. The rate of group B is （47.08±9. 613）%. There exits difference coruparing between any two groups in all. These results have statistical significance. Conclusion In different stages of atherosclerosis, turgor vitalis changes, so it can be quantified by the rate of turgor vitalis. This phe- nomenon accords with the hypothesis of low wall shear stress and provids basis for iconography.