ROC曲线评价超声和MRI对甲状腺良恶性结节的诊断价值

Evaluating the value of ultrasound and MRI in diagnosis of benign and malignant thyroid nodules with ROC curves

目的利用ROC曲线评价超声(ultrasonography,US)和MRI对甲状腺良恶性结节的诊断价值。方法对33例患者的52个甲状腺结节行US及MRI检查,以术后病理结果为金标准,比较两种方法的敏感度、特异度、阳性似然比、阴性似然比和准确率,并绘制ROC曲线。结果 US和MRI诊断甲状腺良恶性结节的敏感度、特异度、阳性似然比、阴性似然比和准确率分别为85.72%、93.55%、13.29、0.15、90.38%和57.14%、83.87%、3.54、1.96、73.08%,两者的曲线下面积分别为0.896、0.705,两者差异具有显著的统计学意义(P<0.05)。结论对甲状腺结节良恶性的诊断,US比MRI更具有一定的优势。

Objective To compare the value of ultrasonography （US） and magnetic resonance image （MRI） in diagnosis benign and malignant thyroid nodules with ROC curves. Methods 33 patients with 52 thyroid nodules were detected by US and MRI, the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and accuracy were compared between the two methods. The results evaluated by using ROC curves. Results The sensitivity, specificity, positive like- lihood ratio, negative likelihood ratio, accuracy of US and MRI for thyroid benign and malignant lesions were 85.72 %, 93.55%, 13.29, 0.15, 90.38% and 57.14%, 83.87%, 3.54, 1.96, 73.08%. The area under ROC curve （AUC） of US and MRI were 0. 896 and 0. 705. There was significant statistical significance between the difference of them （ P〈0.05）. Conclusion In diagnosing benign and malignant thyroid nodules, US, currentl, y has some advantages with respect to MRI.