氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘的临床效果比较

Comparison of Clinical Effect between Oxygen-driven Aerosol and Compressed Air Pump Inhalation for Children Asthma

目的:比较氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘的临床效果,为患儿临床用药提供一定参考依据。方法:选取本院2012年2月-2014年8月收治的哮喘患儿60例为观察组,采用氧驱动雾化吸入治疗,同期选取60例哮喘患儿为对照组,采用空气压缩泵雾化吸入治疗,两组患儿基础治疗和雾化吸入药物均相同,观察两组患儿治疗前后血氧饱和度变化情况及临床效果。结果:治疗后,观察组总有效率为96.7%,明显高于对照组的76.7%,比较差异具有统计学意义(P<0.05);两组患儿治疗前血氧饱和度差异无统计学意义,治疗后观察组血氧饱和度明显高于治疗前,比较差异具有统计学意义(P<0.05);对照组治疗后血氧饱和度与治疗前比较差异无统计学意义(P>0.05);两组患儿治疗后血氧饱和度比较,观察组明显高于对照组,比较差异具有统计学意义(P<0.05)。结论:氧驱动雾化吸入相比空气压缩泵雾化吸入治疗小儿哮喘的临床效果更佳,不仅可以有效缓解患儿咳嗽、胸闷等临床不良症状,还能够明显提高血氧饱和度,改善其缺氧状态,可作为临床治疗小儿哮喘的首选方法。

Objective：To compare clinical effect between oxygen-driven aerosol and compressed air pump inhalation for children asthma, provide a reference for clinical therapy.Method： From 2012 February to 2014 August, 60 children with asthma were chosen as observation group and treated by oxygen-driven aerosol. Another 60 children with asthma in the same period were chosen as control group and treated by compressed air pump inhalation. The basic treatment and aerosol inhalation drugs between the two groups were the same. To compare the change of blood oxygen saturation and clinical effect between the two groups.Result： The overall clinical effect of the observation group was 96.7%, which was significantly higher than 76.7% of the control group, the difference was statistically significant （P〈0.05）. The blood oxygen saturation between the two groups before treatment had no significant difference （P〉0.05）, while the change of blood oxygen saturation in observation group after treatment was significant （P〈0.05）, which had no significant difference after treatment in the control group, blood oxygen saturation after treatment of the observation group was significantly higher than that of the control group, and the difference was statistically significant （P〈0.05）.Conclusion：The clinical effect of oxygen-driven aerosol is higher than compressed air pump inhalation in treatment of bronchial asthmatic children. Oxygen-driven aerosol can relieve the clinical symptoms effectively and improve the blood oxygen saturation significantly which can be used as the preferred method of treatment in bronchial asthmatic children.