摘要
认清急性肾小球肾炎病因及发病机制,对于有效预防、诊断及治疗该病具有重要指导意义。由于人体心、肝、肺等重要脏器位于腹部及胸腔之内,相互紧贴有利于保温,又有骨骼、肌肉、脂肪组织的严密保护,相对能够抵御外界低温的变化,一般不容易受冻造成损害,但肾脏位于腹膜外围,靠近皮下,相对远离其他脏器,故容易受到外界温度等变化的影响。如果人体后腰部受冻时间过长就可能导致肾脏受损,肾脏就会变成靶器官,此时若患上呼吸道感染、机体免疫力下降时,已变成靶器官的肾脏就可能成为被侵害的对象,肾脏就可能发病,这就是通常所谓的急性肾小球肾炎。因此,人体后腰部受冻导致肾脏受损,同时患上呼吸道感染,这两种因素可能是导致急性肾小球肾炎发病的主要原因。
It is of great instructive significance to recognize the etiology and pathogenesis of acute glomerulonephritis for effective prevention, diagnosis and treatment of this disease. Because the human heart, liver, lungs and other organs are located within the abdomen and chest and protected by bone, muscle and adipose tissues, they are not prone to be affected by relatively lower outside temperature or to get cold. However, the kidney is located at the rear of the abdominal cavity in the retroperitoneal space and far from the other organs, so it is easy to be influenced by the ambient temperature. If the location is exposed to cold chronically, the kidney is susceptible to damage, especially when the body is suffering from decreased immunity due to upper respiratory tract infection; as a result, acute glomerulonephritis may develop. Therefore, chronic waist cold that leads to kidney damage and respiratory tract infections that result in low immunity, these two factors may be the main causes of the onset of acute glomerulonephritis.
出处
《医学争鸣》
CAS
北大核心
2015年第5期18-20,共3页
Negative
关键词
急性肾小球肾炎
病因及发病机制
后腰部受冻
上呼吸道感染
acute glomerulonephritis
etiology and pathogenesis
back waist cold
upper respiratory tract infection