白藜芦醇邻甲苯胺衍生物的合成

The synthesis of a derivative of resveratrol and o-methylaniline

目的：开发一种新型白藜芦醇邻甲苯胺衍生物的合成工艺。方法以白藜芦醇为起始反应物，以较简单的方法，经4步反应合成得到目标产物。结果实验依次经过取代反应、水解反应、生成酰氯的反应以及生成酰胺的反应，最终得到收率为69．5％的白藜芦醇邻甲苯胺衍生物。结论本实验中的合成路线具有反应条件温和、产率高等优点。

Objective To develop the synthetic process of a new derivative of resveratrol and o-methylaniline. Methods Using resveratrol as a starting material, four chemical reactions were taken to synthesize the target product. Results The derivative of resveratrol and o-methylaniline was obtained through substitution reaction, hydrolysis reac-tion, acyl chloride-formation reatcion, and amide-formation reaction, with a total yield of 69.5%.Conclusion The reported synthesis route is easy to operate, and can have a high yield under a mild condition.