阻塞性睡眠呼吸暂停低通气综合征与心律失常关系的研究

Analysis of Obstructive sleep apnea hypopnea syndrome and arrhythmia

目的 研究阻塞性睡眠呼吸暂停低通气综合征 （ OSAHS） 与心律失常关系. 方法 对1 861例老年人（男性1 113例、 女性748例） 进行OSAHS调查, 随机对632例采用多导睡眠监测仪监测, 并对所有患者进行常规12导联心电图检查, 分析心律失常情况. 结果 1 861例中OSAHS 541例 （ 29.1%）. OSAHS组最高、 最低心率、 房性心律失常、 交界性和室性早搏、 房室传导阻滞、 ST-T缺血性改变均较对照组差异有统计学意义 （P〈0.05~0.01）. 心律失常和ST-T改变, OSAHS组71.3%、 对照组19.1% （ P〈0.01 ）. 结论 军队干休所老年人OSAHS发生率高, 并且OSAHS组心律失常发生增多. 产生心律失常机理可能与OSAHS引起的缺氧、 自主神经功能紊乱、 多系统器官损害等有关.

Objective Analysis of Obstructive sleep apnea hypopnea syndrome（ OSAHS） and arrhythmia.Methods 1 861 cases of elderly（1 113 cases of male and female 748 cases）were OSAHS investigation,632 cases randomly using polysom-nography was monitored,and all patients routine 12-lead ECG,arrhythmia analysis.Results 1 861 cases of OSAHS 541 patients （29.1%）.Highest OSAHS group,the lowest heart rate,atrial arrhythmia,borderline and premature ventricular contractions,atrio-ventricular block,ST-T ischemic changes than the control group there was significant difference（P＆lt;0.05~0.01）.Arrhythmia and ST-T changes,OSAHS group 71.3%,control group 19.1%（P＆lt;0.01）.Conclusion Elderly high incidence of OSAHS army re-tired cadres and OSAHS group increased arrhythmia.Generating mechanism may be associated with OSAHS hypoxia arrhythmia caused by autonomic dysfunction,multi-system organ damage and so on.