期刊文献+

认知双任务对早期帕金森病患者姿势稳定性及手灵活性的影响 被引量:1

The effect of dual-task interference on postural sway and hand flexibility in early Parkinson's disease
原文传递
导出
摘要 目的 研究认知双任务对早期帕金森病(Parkinson's disease,PD)患者姿势稳定性及手灵活性的影响.方法 选择23例早期PD患者为PD组,Hohn-Yahr(H-Y)分期为1~1.5期.23例性别和年龄匹配的健康受试者为对照组,其均无PD病史.摆动参数的测量由可佩戴惯性加速计来完成.主要计算来自加速计信号的两个姿势摆动参数:(1)均方根加速度(root mean square acceleration,RMS);(2)急动度(jerkiness of sway,JERK).手灵活性的测量由普渡钉板完成,比较两组间对应钉子数.结果 在常规状态下,PD组与对照组各摆动参数之间比较均差异无统计学意义(P>0.05).在执行认知双任务状态下,两组RMS值[睁眼双任务:PD组(0.156±0.112) m/s2,对照组(0.086±0.026) m/s2;闭眼双任务:PD组(0.204±0.162) mr/s2,对照组(0.095±0.023) m/s2]差异有统计学意义(P<0.01).在执行认知双任务状态下,总JERK值,前后(AP)方向和左右(ML)方向JERK值,PD患者均高于对照组(P<0.05).PD组患者在30 s内放入的钉子数[(17.33±4.87)个]较对照组[(20.77±4.13)个]少,差异有统计学意义(P<0.05).结论 早期PD患者手的灵活性明显下降.早期PD患者在站立的同时执行一个需求认知任务将会威胁到其平衡的稳定性. Objective To observe the effect of dual-task interference on postural sway and hand flexibility of patients with early Parkinson's disease (PD).Methods Twenty-tree patients with early PD and twcnty-three healthy,sex-and age-matched control subjects were examined.Postural sway was measured with an accelerometer at the centre of mass at the lower spine.Two parameters of postural sway were computed from the acceleration signals including root mean square acceleration (RMS) and jerkiness of sway (JERK).Purdue pegboard test,single-task tests and dual-task test were performed respectively to record the numbers of nails inserted with left hand,right hand and both hands within 30 seconds.Results In the usual conditions,no significant differences of postural sway parameters were found between the control group and PD group in eye open and eye closed condition.In dualtask condition,PD patients showed an increase of RMS values (eye open conditions:PD group (0.156±0.112) m/s2,control group (0.086±0.026) m/s2;eye closed conditions:PD group (0.204±0.162)m/s2,control group (0.095±0.023)m/s2) of sway acceleration,compared with control subjects (P〈0.01).These differences reached significance during cognitive task performance in eye open and eye closed with dual task.PD patients showed larger JERK values with increasing difficulty of the sway task which also reached significance during cognitive task performance(P〈0.05).The number of pegs inserted within 30 s in patients with PD (17.33±4.87)was significantly lower than that in controls (20.77±4.13) (P〈0.05).Conclusion The hand flexibility of patients with early PD obviously decrease.The balance of patients with early PD may deteriorate when their attention is diverted or reduced because of attempting to perform cognitive tasks.
出处 《中华行为医学与脑科学杂志》 CAS CSCD 北大核心 2015年第11期1008-1011,共4页 Chinese Journal of Behavioral Medicine and Brain Science
关键词 帕金森病 姿势稳定性 认知双任务 加速计 Parkinson's disease Postural instability Dual-task interference Accelerometer
  • 相关文献

参考文献21

  • 1Aarsland D, Andersen K, Larsen JP, et al. Risk of dementia in Parkin- son's disease: a community-based, prospective study [ J ]. Neurology, 2001,56(6) :730-736.
  • 2于翠玉,刘卫国,陈伶,冯芜若.帕金森病患者认知功能两年随访[J].中华行为医学与脑科学杂志,2014,23(7):601-604. 被引量:7
  • 3Lee JM, Koh SB, Chae SW, et al. Postural instability and cognitive dys- function in early Parkinson's disease [ J 1. Can J Neurol Sci, 2012,39 (4) :473-482.
  • 4Fraizer EV,Mitra S. Methodological and interpretive issues in posture-cogni- tion dual-tasking in upright stance[J]. Gait Pesture,2[308,27(2) :271-279.
  • 5Mancini M, Horak FB, Zampieri C, et al. Trunk accelerometry reveals postural instability in untreated Parkinson's disease [ J ]. Parkinsonism Relat Disord, 2011,17 (7) : 557-562.
  • 6Mancini M, Salarian A, Carlson-Kuhta P, et al. ISway : a sensitive,val- id and reliable measure of postural control [ J]. J Neuroeng Rehabil, 2012,9:59.
  • 7Frenklach A, Louie S, Koop MM, et al. Excessive postural sway and the risk of falls at different stages of Parkinson's disease[J]. Mov Disord, 2009,24 (3) : 377-385.
  • 8Schubert T, Volkmann J, Muller U, et al. Effects of pallidal deep brain stimulation and levodopa treatment on reaction-time performance in Parkinson's disease[ J]. Exp Brain Res,2002,144( 1 ) :8-16.
  • 9Marchese R, Bove M, Abbruzzese G. Effect of cognitive and motor tasks on postural stability in Parkinson's disease: a posturographic study [ J ]. Mov Disord, 2003,18 (6) : 652-658.
  • 10Chung KA, Lobb BM, Nutt JG, et al. Objective measurement of dyski- nesia in Parkinson's disease using a force plate [ J ]. Mov Disord,2010, 25 ( 5 ) : 602-608.

二级参考文献46

  • 1陈双庆,蔡庆,沈玉英,赵中,周华.轻度认知功能损害患者扣带后回谷氨酸多体素氢质子磁共振波谱研究[J].中华诊断学电子杂志,2013,1(1). 被引量:33
  • 2Gray P,Hildebrand K. Fall risk factors in Parkinson's disease. J Neu- rosci Nurs ,2000,32:222-228.
  • 3Bastiaan RB,Jeffrey MH. Falls and freezing of gait in parkinson's dis- ease:a review of two interconnected episodic phenomena. Mov Dis Soc,2004,19:871-884.
  • 4Coppin AK,Shumway-Cook A, Saczynski JS, et al. Association of ex- ecutive function and performance of dual-task physical tests among older adults:analyses from the In-Chianti study. Age Ageing,2006,35: 619-624.
  • 5Gilles Allali , Frederic Assal, Reto W. Kressig, el at. Impact of im- paired executive function on gait stability. Dement Geriatr Cogn Dis- ord, 2008,26 : 364 -369.
  • 6Brown RG, Marsden CD. An investigation of the phenomenon of " set" in Parkinson's disease. Mov Disord,1988 ,3 :152-61.
  • 7Gelb I)J, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch. Neurol, 1999,56 : 33 -39.
  • 8All S, John GN, Bruce RR. Parkinson's disease. Lancet,2004,363 : 1783-1793.
  • 9Sehaafsma JD,Giladi N,Balash Y,et al. Gait dynamics in Parkinsong disease:relationship to Parkinsonian features, falls and response to levodopa. Neurol Sci,2003,212:47-53.
  • 10Goetz CG,Poewe W,Rascol O,et al. Movement disorder society task force report on the Hoehn and Yahr staging seale: status and recom- mendations. Mov Disord,2004,19 : 1020-1028.

共引文献10

同被引文献6

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部