摘要
目的:探讨ACTN3基因R577X多态性频率分布在不同运动项目选材中的应用及相关性的研究。方法:应用荧光实时定量PCR法对西安体育学院112名一级和二级运动员与西北大学120名普通学生进行对比研究,分析ACTN3基因多态性频率分布特点。结果:ACTN3基因R577X多态位点分布频率符合Hardy-Weinberg平衡。ACTN3基因R577X杂合子R/X基因型频率为71.4%,纯合子R/R为22.3%,X/X为6.3%,R/X基因型显著性多于XX基因型(P<0.05),ACTN3基因R577X多态位点R等位基因频率为58%,显著高于X等位基因频率42%(P<0.05)。结论:ACTN3基因R577X基因型与运动能力相关,速度和力量性项目表现与577R等位基因相关,耐力性项目表现与577X等位基因相关,从而为运动项目选材和运动员的科学训练提供参考依据。
Objective： To investigate the frequency distribution ACTN3 gene R577X polymorphism in the application and correlation of selection of different sports. Methods： Real-time PCR method for Xi＇an Institute of Physical Education 112 Primary and secondary athletes and regular students at Northwestern University 120 comparative study, analysis ACTN3 gene polymorphism frequency distribution characteristics. Results： ACTN3 gene R577X frequency distribution ofpolymorphic loci in Hardy-Weinberg equilibrium. ACTN3 gene heterozygous R577X R / X genotypes were 71.4%, homozygous R / R was 22.3%, X / X was 6.3%, R / X genotype significantly more than XX genotype （P 〈0.05 ） , ACTN3 gene R577X polymorphism loci R allele frequency was 58%, significantly higher than the X allele frequency 42% （ P 〈0.05 ） . Conclusion： ACTN3 gene R577X genotypes associated with athletic ability, speed and power project performance and 577R allele, Endurance performance and 577X allele, so as to provide reference for scientific selection and training of sports athletes.
出处
《四川体育科学》
2015年第6期37-40,共4页
Sichuan Sports Science
基金
陕西省体育局常规课题(15019)
