精神分裂症采用利培酮联合改良电抽搐疗法治疗的效果分析

Effect of Risperidone Combined with Modified Electroconvulsive Therapy in the Treatment of Schizophrenia

目的观察精神分裂症采用利培酮联合改良电抽搐疗法治疗的临床效果。方法选取我院2013年11月至2014年11月收治的76例精神分裂症患者为研究对象,按随机数字表法将患者分为观察组与对照组各38例。对照组患者使用利培酮口服液治疗,观察组患者在此基础上联合改良电抽搐疗法治疗。观察比较两组的临床效果和不良反应发生情况。结果观察组治疗总有效率为89.47%,显著高于对照组的71.05%,两组比较差异有统计学意义(P<0.05)。观察组不良反应发生率为18.42%,显著低于对照组的39.47%,两组比较差异有统计学意义(P<0.05)。结论采用利培酮联合改良电抽搐疗法治疗精神分裂症患者效果确切,安全性高,适合于临床推广。

Objective To observe the clinical effect of risperidone combined with modified electroconvulsive therapy （MECT） in the treatment of schizophrenia. Methods 76 cases of patients with schizophrenia treated in our hospital from November 2013 to November 2014 were selected as research objects. According to the random number table method, the patients were divided into control group （38 cases） and observation group （38 cases）. The control group was treated with risperidone oral solution, while the observation group was treated with modified electroconvulsive therapy on this basis. The incidence of adverse reactions and treatment effect of two groups were observed and compared. Results The total effective rate of observation group was 89.47%, significantly higher than 71.05% of control group, with statistical difference （P 〈0.05）; the incidence of adverse reactions of observation group was 18.42%, significantly lower than 39.47% of control group, with statistical difference （P〈0.05）. Conclusions The effect of risperidone combined with modified electroconvulsive therapy in the treatment of schizophrenia is accurate, with high safety. The method is suitable for clinical application.