高血压患者颈动脉斑块与血压变异的相关性

Correlation between carotid plaque and blood pressure variation in patients with hypertension

目的探讨高血压患者颈动脉斑块的发生与血压变异性的相关性。方法入选181例住院高血压患者,经颈动脉超声检查分为颈动脉斑块组(研究组)和无斑块组(对照组),对2组患者进行24小时动态血压检测,计算并比较2组白天以及夜间的血压变异系数。结果高血压合并颈动脉斑块组的白天收缩压变异系数及舒张压变异系数大于对照组,差异有统计学意义(P<0.05)。结论高血压患者颈动脉斑块的发生与白天血压变异性有密切的相关性。

Objective To investigate the correlation between carotid plaque and blood pressure variation（BPV）in patients with hypertension.Methods The study enrolled 181 patients with hypertension who were divided into plaque group and non-plaque group according to the results of carotid artery ultrasonography.All patients were measured by ambulatory blood pressure monitoring.The mean blood pressure,mean pulse pressure,blood pressure variation coefficient of two groups were calculated and compared during daytime and nighttime.Results The systolic blood pressure coefficient of daytime in plaque group was higher than that of non-plaque group.The diastolic blood pressure coefficient of daytime in plaque group was also higher than that of non-plaque group.Conclusion The occurrence of carotid plaque in patients with hypertension is closely correlated to blood pressure coefficient of daytime.