摘要
The authors describe the clinical presentation of a 59-year old woman in the emergency room, with agitation, confusion and hypothermia. She was previously diagnosed with hypothalamic-pituitary insufficiency with complete dysfunction of the pituitary gland, poikilothermia and central diabetes insipidus, treated with hormone supplements. In the emergency room, she showed a dysregulation in temperature, altered mental status and hyponatremia. The differential diagnosis was hypothermia based on infection with the history of poikilothermia, with dysregulation of her diabetes insipidus. Poikilothermia is an extremely rare condition in humans in which the body temperature variates with the surrounding temperature. Dysregulation may develop due to different causes.