居家养老帕金森病人非运动症状对认知功能的影响

The Impact of Non-movement Symptoms on Cognitive Function of Parkinson Patients in Home Care for the Aged

目的:探讨居家养老的帕金森病人非运动症状与认知功能之间的关系。方法:收集2014-2015年居家养老平台登记的帕金森病人,选择帕金森痴呆48人,轻度认知障碍73人,正常认知的PD病人52人,三组分别进行单因素和多因素分析。结果:PDD、MCI、PD平均年龄为75.44、70.86、70.35。非运动症状在PD的发生率高。结论:PDD和MCI的发生与疼痛、排便异常感和注意力有关。

Objective：To investigate the relationship between non-motor symptoms and cognition in Pakinson＇s disease.Methods：We conducted a case-control study among the PD patients and MCI patients in PD registered in the data base of home-based care for the aged from 2014 to 2015.Forty-eight PDD 73 MCI and 52 normal cognitive PD were selected.Each case-control group was matched for gender and education degree.Univariate and multivariate analyses were conducted using Logistic regression model.Results：The mean age of PDD group was 75.44 years old and 70.35 years old in normal cognitive PD group,while 70.86 years old in MCI group.The incidence of non-motor symptoms were high in PD.Conclusions：The cognitive impairment in PDD and MCI related with pain,paresthesia after defecation,attention.