中药内服外洗治疗膝骨关节炎临床观察

Clinical Observation on the Treatment of Knee Osteoarthritis by Oral Administration of and External Washing with Traditional Chinese Medicine

目的:观察中药内服外洗治疗膝骨关节炎的临床疗效。方法:将180例膝骨关节炎患者随机分为治疗组和对照组,每组90例。对照组服用硫酸氨基葡萄糖胶囊每次0.3 g,每日3次;双氯芬酸钠缓释胶囊每次0.1 g,每日1次。治疗组在对照组治疗的基础上加用中药内服及局部外洗。两组均以30 d为1个疗程。观察两组临床疗效及膝关节功能分级、疼痛分级。结果:治疗组治愈13例,显效65例,有效8例,无效4例,总有效率为95.56%;对照组治愈4例,显效25例,有效31例,无效30例,总有效率为66.67%。两组比较,差异有统计学意义(P<0.05)。治疗后,两组膝关节功能分极、疼痛分级较治疗前均有改善(P<0.05),且治疗组均优于对照组(P<0.05)。结论:中药内服外洗联合运用治疗膝骨关节炎有明显疗效,值得进一步推广应用。

Objective：To observe the clinical effect of treating knee osteoarthritis by oral administration of and external washing with traditional Chinese medicine（TCM）.Methods：180 cases of knee osteoarthritis were randomly divided into a treatment group and a control group,90 cases in each.Patients in the control group were given Glucosamine Sulfate Capsules,0.3 g each time,3 times a day;and Diclofenac Sodium Sustained Release Capsules,0.1 g each time,once a day.Based on the treatment of the control group,the treatment group was treated by oral administration of and external washing with TCM.The two groups were treated with30 days as 1 course,observing their clinical efficacy,knee joint functional classification and pain grading.Results：In the treatment group,13 cases were cured,65 cases were markedly effective,8 cases were effective,and 4 cases were invalid,the total effective rate being 95.56%;while in the control group,4 cases were cured,25 cases were markedly effective,31 cases were effective,and 30 cases were ineffective,the total effective rate being 66.67%.The difference between the two groups was statistically significant（P 〈 0.05）.After treatment,the knee joint functional classification and pain grading of the two groups were improved compared with those before the treatment（P 〈 0.05）,and the treatment group was better than the control group（P 〈 0.05）.Conclusion：Oral administration of and external washing with TCM in the treatment of knee osteoarthritis has an obvious curative effect,it is worthy of further popularization and application.