肖承悰辨证治疗多囊卵巢综合征120例临床观察

Clinical observation on 120 cases of polycystic ovarian syndrome with syndrome differentiation based treatment by XIAO Chengcong

目的观察肖承悰教授辨证治疗多囊卵巢综合征(PCOS)的临床疗效。方法 120例PCOS患者,根据中医辨证分型给予中药口服,1个月为1个疗程,共3个疗程。治疗结束后评价临床疗效、血清性激素水平及体征的改善情况。结果治疗后临床总有效率为88.33%,中医证候总有效率为94.17%;各中医证型之间比较,临床总有效率、中医证候总有效率差异均无统计学意义(P>0.05)。血清睾酮(T)、黄体生成素(LH)水平及LH/卵泡刺激素(FSH)比值均较治疗前明显下降(P<0.01,P<0.05)。体质指数、多毛、痤疮均较治疗前明显改善(P<0.05),尤以痤疮改善最为明显(P<0.01)。结论肖承悰教授运用口服中药辨证治疗PCOS疗效确切,且可显著改善血清性激素水平和体征。

Objective To observe the clinical effect on polycystic ovarian syndrome（ PCOS） with syndrome differentiation based treatment by Prof. XIAO Chengcong. Methods 120 cases of PCOS patients were given different herbal medicines orally according to differentiation of syndromes. One month was one course of treatment,and 3 courses in all. Then after treatment ended,the clinical effect,serum sexual hormone and improvement of signs were evaluated. Results The total clinical effective rate after the treatment was88. 33%,the total TCM syndrome effective rate was 94. 17%. To compare the TCM syndromes, the differences in total clinical effectiveness and the total TCM syndrome effective rate had no statistical significance（ P〈0. 05）. Serum testosterone（ T）,luteinizing hormone（ LH）,LH / follicle stimulating hormone（ FSH） were reduced more obviously than that before the treatment（ P〈0. 01,P〈0. 05）. Constitutional Index,polytrichia and acne had been improved（ P〈0. 05）,especially acne improved most obviously（ P〈0. 01）. Conclusion Prof. XIAO Chengcong had treated PCOS with orally taken herbal medicines based on differentiation of syndromes with assured effect,and serum hormone and signs can be improved obviously.