口腔矫正器治疗儿童阻塞性睡眠呼吸暂停综合征的疗效观察

Observation on the efficacy of oral appliance in the treatment of children with obstructive sleep apnea syndrome

目的观察口腔矫正器治疗儿童阻塞性睡眠呼吸暂停综合征的疗效，为相关病症的治疗提供借鉴和参考。方法选取2013年12月～2015年1月我院收治的阻塞性睡眠呼吸暂停综合征患儿15例为研究对象，对比患儿治疗前后呼吸睡眠暂停低通气指数（AHI）、最长呼吸暂停时间（LAT）及血氧饱和度（SPO2）的变化情况；监测并对比患儿治疗前后氮-乙酰天门冬氨酸／肌酸（NAA／Cr）及氮．乙酰天门冬氨酸／胆碱（NAA／Chr）。结果对比发现，患儿治疗后较治疗前各个项目均有明显改善，差异有统计学意义（P〈0．05）。结论矫治器是一种有效治疗儿童阻塞性睡眠呼吸暂停综合征的方法，值得临床推广应用。

Objective To study the clinical effect of the treatment of children with obstructive sleep ipnea syndrome, and to provide reference for the treatment of related diseases. Methods From January 2015 to December 2013, 15 cases of obstructive sleep apnea syndrome in our hospital were selected.The changes of SPO, LAT and AHI before and after treatment were compared. Monitor and compare the NAA/Cr and ）4AA/Chr before and after treatment. Results The comparison showed that the treatment was significantly reproved after treatment, the difference was significant （P〈0.05）. Conclusion Appliance is an effective means for clinical treatment of children with obstructive sleep apnea syndrome.