1Chen KH, Dasgupta A, Ding J, et al. Role of Mitofusin 2(Mfn2) in controlling cellular proliferation[J]. FASEB J, 2014, 28:382-394.
2Misko AL, Sasaki Y, Tuck E, et al. Mitofusin2 mutations disrupt ax-onal mitochondrial positioning and promote axon degeneration[J]. J Neurosci, 2012, 32:4145-4155.
3Guo X, Chen KH, Guo Y, et al. Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway[J]. Circ Res, 2007, 101:1113-1122.
4HemOndez-Alvarez MI, Thabit H, Bums N, et al. Subjects with ear- ly- onset type 2 diabetes show defective activation of the skeletal muscle PGC-1 {alpha}/Mitofusin-2 regulatory pathway in response to physical activity[J]. Diabetes Care, 2010, 33:645-651.
5Wu L, Li Z, Zhang Y, et al. Adenovirus-expressed human hyperpla- sia suppressor gene induces apoptosis in cancer ceils [J]. Mol, Can- cer Ther, 2008, 7:222-232.
6Sebastidn D, Hemrndez-Alvarez MI, Segal6s J, et al. Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis[J]. Proc Natl Acad Sci U S A, 2012, 109:5523-5528.
7Mufioz JP, Ivanova S, Sanchez-Wandelmer J, et al. Mfn2 modulates the UPR and mitochondrial function via repression of PERK[J]. EM- BO J, 2013, 32:2348-2361.
8Mufioz JP, Zorzano A. Mfn2 modulates the unfolded protein response [J]. Cell Cycle, 2014, 13:491-492.
9Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress[J]. Nat Cell Biol, 2011, 13:184-190.
10Ctrdenas C, Miller RA, Smith I, et al. Essential regulation of cell bioenergetics hy constitutive InsP3 receptor Ca2+ transfer to mito- chondria[J]. Cell, 2010, 142:270-283.
5SANTEL A, FULLER M T. Control of mitochondrial morphology by a human mitofusin[J]. J Cell Sci, 2001, 114(Pt 5) : 867- 874.
6CHEN K H, GUO X M, MAD L, et al. Dysregulation of HSG triggers vascular proliferative disorders[J]. Nat Cell Biol, 2004, 6(9) : 872-883.
7JIANG G J, HAN M, ZHENG B, et al. Expression and function of hypertension related gene hrg-1 during redifferentiation of vascular smooth muscle cells [J]. Heart Vessels, 2006, 21 (5): 315- 320.
8JIANG G J, PANL, HUANG X Y, et al. Expression of HSG is essential for mouse blastocyst formation [ J ]. Biochem Biophys Res Commun, 2005, 335(2): 351-355.
9SORIANO F X, LIESA M, BACH D, et al. Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferatoractivated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2 [ J ]. Diabetes, 2006, 55 ( 6 ) : 1783-1791.
10SKULACHEV V P. Mitochondrial filaments and dusters as intracellular power-transmitting cables[J]. Trends Biochem Sci, 2001 , 26 ( 1 ) : 23-29.
5SRINIVASAN R, RICKETTS CJ, SOURBIER C, et al. New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease[J]. Clin Cancer Res, 2015, 21(1):10-17.
6CHEN KH, DASGUPTA A, DING J, et al. Role of Mitofusin 2(Mfn2) in controlling cellular proliferation[J]. FASEB J, 2014, 28(2):382-394.
7SU D, SINGER EA, SRINIVASAN R. Molecular pathways in renal cell carcinoma: recent advances in genetics and molecular biology[J]. Curr Opin Oncol, 2015, 27(3):217-223.