新疆地区细菌性肺炎患者血清炎症指标研究

Study of serum inflammatory markers in bacterial pneumonia patients in Xinjiang region

目的探讨新疆地区细菌性肺炎与血清高敏C反应蛋白(hs-CRP)、白细胞介素6(IL-6)、降钙素原PCT的关系。方法收集2014年2月-2014年10月我院确诊为细菌性肺炎患者100例为病例组,选择同期体检健康者100例为对照组,分析新疆不同民族、不同性别细菌性肺炎患者血清中hs-CRP、IL-6、PCT浓度的差异。结果 (1)新疆地区维族、汉族细菌性肺炎患者血清中hs-CRP、IL-6、PCT浓度高于相应健康对照组,差异有统计学意义(P<0.05)。(2)新疆地区男性、女性细菌性肺炎患者血清中hs-CRP、IL-6、PCT浓度高于相应健康对照组,差异有统计学意义(P<0.05)。结论新疆地区hs-CRP、IL-6、PCT浓度能为细菌性肺炎提供诊断信息,是临床肺部感染诊断的重要辅助手段。

Objective To explore the association between bacterial pneumonia and hypersensitive C reactive protein（hs-CRP）,interleukin-6and procalcitonin in Xinjiang region,China.Methods 100 patients with bacterial pneumonia diagnosed by our hospital were taken as the case groups,another 100 healthy people were collected as the control group.The difference of their serum hs-CRP、IL-6、PCT level were analysed in different ethnicities and gender.Results（1）The concentrations of serum hs-CRP,IL-6、PCT in Han and Uygur bacterial pneumonia patients in Xinjiang region were significantly higher than that in corresponding control group（P〈0.05）.（2）The concentrations of serum hs-CRP,IL-6、PCT in male and female bacterial pneumonia patients in Xinjiang region were significantly higher than that in corresponding control group（P〈0.05）.Conclusion Serum hs-CRP、IL-6、PCT level can provide diagnostic information for bacterial pneumonia,and is an important supplementary means for diagnosis of pulmonary infection.