D-二聚体检测联合超声检查在妇科肿瘤术后下肢深静脉血栓诊断中的应用

The Diagnosis Plasma D-dimer Test and Color Doppler Ultrasound of Deep Vein Thrombosis in Postoperative Gynecologic Oncology Patients

目的探讨血浆D-二聚体检测联合彩色多普勒超声检查对诊断妇科肿瘤术后患者下肢深静脉血栓形成的诊断价值。方法对常规妇科肿瘤术后患者156例行常规下肢静脉超声检查及血浆D-二聚体浓度检测,判断有无下肢深静脉血栓形成。结果血浆D-二聚体检测和彩色多普勒超声检查诊断妇科肿瘤术后患者下肢深静脉血栓的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为83.87%、66.66%、83.87%、100.00%、89.10%和96.80%、83.30%、96.80%、83.30%和94.60%。彩色多普勒超声检查的特异性、准确性及阳性预测值高于血浆D-二聚体浓度测定;血浆D-二聚体检测较彩色多普勒超声检查具有较高的阴性预测值。结论血浆D-二聚体检测联合彩色多普勒超声可以准确地评估妇科肿瘤患者术后下肢静脉血栓的形成情况,具有较高的临床应用价值。

OBJECTIVE To evaluate the value of diagnosis of deep vein thrombosis in postoperative gynecologic oncology patients taking plasma D-dimer test and color Doppler ultrasound.METHODS Routine postoperative gynecologic oncology patients 156 cases which were diagnosis with plasma D-dimer test and ultrasonography to determine the deep vein thrombosis.RESULTS Plasma D-dimer test and color Doppler ultrasound in diagnosis of deep vein thrombosis in postoperative gynecologic oncology patients,the sensitivity,specificity,positive predictive value,negative predictive value and accuracy were 83.87%,66.66%,83.87%,100.00%,89.10%and 96.80%,83.30%,96.80%,83.30%,94.60%.Specificity and positive predictive value of color Doppler ultrasound were higher than plasma D-dimer test in diagnosis of deep vein thrombosis in postoperative gynecologic oncology patients,but the plasma D-dimer test had a higher negative predictive value in diagnosis of deep vein thrombosis in postoperative gynecologic oncology patients.CONCLUSION The methods of plasma D-dimer test and color Doppler ultrasound could accurately assess deep vein thrombosis in postoperative gynecologic oncology patients,which had a high clinical value.