C反应蛋白与外周血白细胞检测在社区小儿呼吸道感染诊治中的应用

The Detection Value of C Reactive Protein Combined with Peripheral White Blood Cell in the Clinical Diagnosis of Respiratory Tract Infections in Community Children

目的探讨C反应蛋白(CRP)联合外周血白细胞(WBC)检测,对社区诊治小儿呼吸道感染的价值。方法纳入细菌性呼吸道感染患儿(A组)、病毒性呼吸道感染患者(B组)、健康体检儿(C组)各30例。行血常规检测WBC水平,行免疫比浊法检测其CRP水平。行对比分析。结果 (1)A组WBC明显高于B组及C组(P<0.05);A组CPR明显高于B组,并明显高于C组,两两对比,差异均有统计学意义(P<0.05);(2)ROC曲线指出CRP与WBC对诊断小儿呼吸道感染及鉴别病原菌均有指导价值(P<0.05),且CRP对诊断的最佳界值为4.77 mg/L,对鉴别的最佳界值为8.62mg/L,WBC相应为5.23×109/L和7.90×109/L。结论 C反应蛋白与外周血白细胞水平对鉴别诊断小儿呼吸道感染均有一定价值。

Objective To investigate the value of C reactive protein （CRP） combined with detection of peripheral white blood cell （WBC） in the clinical diagnosis of respiratory tract irtfections in community children. Methods 30 children with bacterial respir- atory tract infections （group A） , 30 children with viral respiratory tract infections （group B） and 30 healthy children （group C） were selected. The routine blood test for WBC levels was carried out and CRP level was detected by immune assay. The results of the detec- tion were compared and analyzed. Results （ 1 ） WBC level in group A was significantly higher than that in group B and group C （ P 〈 0. 05 ） , CPR level in group A was significantly higher than that in group B and group C and the differences were statistically signifi- cant （P 〈 0. 05 ）. （2） Tile ROC curve indicated that WBC and CRP had guiding value in diagnosing respiratory tract infections in chil- dren and identifying pathogenic bacteria （ P 〈 0. 05 ）. The best diagnostic value for CRP was 4. 77 mg/L, the best cutoff value for CRP was 8.62 rag/L, and WBC was 5.23 × 10^9/L and 7.90 × 10^9/L. Conclusion C reactive protein and the level detection of peripheral white blood cell have certain value in the clinical diagnosis of respiratory tract infections in children.