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糖氨基酸化合物的合成研究

Synthesis of glycopeptides
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摘要 目的本文对糖氨基酸化合物的反应进行了研究。方法葡萄糖醛酸在四氢呋喃中与RGDV寡肽反应。结果反应得到糖肽化合物。结论与寡肽反应生成含糖基的四肽产物。 Objective The synthesis of glycopeptide was investigated. Methods The reaction of glucuronic acid with peptide was performed in tetrahydrofuran. Results Glucuronic acid reacted with peptide to form glycopeptide. Conclusion Thus we have explored the reaction of glucuronic acid with peptide. Tetra-peptide was obtained containing glycosylation.
作者 曾莉 张建伟
出处 《首都医科大学学报》 CAS 北大核心 2015年第6期921-923,共3页 Journal of Capital Medical University
基金 国家自然科学基金(20642004)~~
关键词 葡萄糖醛酸 寡肽 糖基化 glucuronic acid peptide glycosylation
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参考文献14

  • 1Yu X, Xia W, Li S A, et al. Antitumor effect and underly- ing mechanism of RGD-modified adenovirus mediated IL-24 expression on myeloid leukemia cells [ J ]. Int Immunop- harmacol, 2015,28 ( 1 ) :560-570.
  • 2Zhu J, Fu F, Xiong Z, et al. Dendrimer-entrapped gold nanoparticles modified with RGD peptide and alpha-tocoph- eryl succinate enable targeted theranostics of cancer cells [ J ]. Colloids and Surf B Biointerfaces, 2015,133 ( 1 ) :36- 42.
  • 3Chang M L, Lu S S, Zhang F, et al. RGD-modified pH- sensitive liposomes for docetaxel tumor targeting [ J ]. Colloids Surf B Biointerfaces, 2015,129 : 175-182.
  • 4Oliveira E A, Faintuch B L. Radiolabeling and biological e- valuation of the GX1 and RGD-GX1 peptide sequence for angiogenesis targeting[ J ]. Nucl Med Biol, 2015,42 ( 2 ) : 123-130.
  • 5Guo Z, He B, Jin H, et al. Targeting efficiency of RGD- modified nanocarriers with different ligand intervals in re- sponse tointegrin αvβ3 clustering[ Jl. Biomaterials, 2014, 35(23) :6106-6117.
  • 6Zhang J, Zhao M, Peng S. Synthesis of mimetic peptides containing glucosamine [ J ]. Carbohydr Res, 2011,346 ( 13 ) : 1977- 2003.
  • 7任丽,刘洋,梁远军,程卯生.糖肽的化学合成研究进展[J].中国药物化学杂志,2012,22(2):142-154. 被引量:1
  • 8Corcilius L, Santhakumar G, Stone R S, et al. Synthesis of peptides and glycopeptides with polyproline II helical topoi- ogy as potential antifreeze molecules [ J ]. Bioorg Med Chem, 2013,21 (12) :3569- 3581.
  • 9Kishore G, Gautam V, Chandrasekaran S. Novel synthesis of carbohydrate fused α-amino γ-lactams and glycopeptides by NIS mediated ring opening of donor-aeceptor substituted cyclopropanes [ J ]. Carbohydr Res, 2011,390 : 1 -8.
  • 10UI-Islam M, Ha J H, Khan T, et al. Effects of glucuronic acid oligomers on the production, structure and properties of bacterial cellulose [ J ]. Carbohydr Polym, 2013,92 ( 1 ) : 360-366.

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