康艾注射液在胃癌化疗中的应用价值研究

Research on the value of Kang'ai injection on gastric cancer patients' chemotherapy

目的:分析康艾注射液在胃癌化疗中的应用价值。方法:选择128例接受化疗的胃癌患者,将其随机分为对照组和观察组,每组64例。对照组接受常规化疗,观察组接受康艾注射液化疗,比较两组化疗后的近期疗效、免疫功能指标及生活质量评分等情况差异。结果:①观察组患者接受化疗后的完全缓解及部分缓解概率均明显高于对照组患者,差异有统计学意义(χ~2=2.471,χ~2=2.748;P<0.05);②观察组患者接受化疗后的IL-6、TNF-α、CD3^+、CD4^+值明显高于对照组患者,CD8^+值明显低于对照组患者,差异有统计学意义(t=2.627,t=2.462,t=2.748,t=2.846,t=2.735,P<0.05);③化疗前两组患者的生活质量评分相比,差异无统计学意义(t=0.462,P>0.05),化疗后各个时期观察组患者的生活质量评分均明显高于对照组患者,差异有统计学意义(t=2.637,t=2.647,t=2.983;P<0.05)。结论:康艾注射液可以显著提高胃癌患者的化疗效果,优化机体免疫功能,同时提高化疗后生活质量。

Objective：To analyze the value of Kang＇ai injection on gastric cancer patients＇ chemotherapy.Methods：Chosen gastric cancer patients with chemotherapy between December 2012 to December 2013 in our hospital as study subject,randomly divided into control group received conventional chemotherapy and observation groups received Kang＇ai injection combine with chemotherapy,compared term effect after chemotherapy,immune function and quality of life scores.Results：l）Observation group patients＇ complete remission and partial remission after chemotherapy were significantly higher than control group patients（χ^2=2.471,χ^2=2.748;P〈0.05）;2）Observation group patients＇ IL-6,TNF-α,CD3^＋,CD4^＋ value was significantly higher than control group after receiving chemotherapy,CD8~＋value was significantly lower than control group patients（t=2.627,t=2.462,t=2.748,t=2.846,t=2.735;P〈0.05）;3）two groups of patients＇ life quality scores before chemotherapy was no significant,after chemotherapy observation group patients＇ life quality scores were significantly higher than control group patients（t=2.637,t=2.647,t=2.983;P〈0.05）.Conclusion：Kang＇ai injection can significantly improve the effectiveness of chemotherapy in patients with gastric cancer,and optimize immune function,while improving the quality of life after chemotherapy.