控制性降压在嗜铬细胞瘤围麻醉期的研究进展

The Progress of Controlled Hypotention Used in Anesthesia of Pheochromocytoma

嗜铬细胞瘤是以分泌儿茶酚胺为主、来源于肾上腺髓质的罕见内分泌肿瘤,外科手术为其主要治疗方式。近年来,尽管增加了对嗜铬细胞瘤生理特点及外科手术期间临床表现的认识,但其罕见的血流动力学变化仍是麻醉医师的挑战。围术期恰当时机应用控制性降压技术可明显减少嗜铬细胞瘤患者术中失血量和输血量、改善术野质量,使围术期血流动力学更稳定,并减少术后并发症的发生。

Pheochromocytoma is a rare secreting tumors from the adrenal medulla,which mainly releases catecholamine. Surgery is the primary treatment for pheochromocytoma. Its rare hemodynamic changes is still challenging the anesthesiologists in spite of our improved understanding of its physiological and clinical behavior during surgery. Rational application of controlled hypotension techniques during operation can not only minimize preoperative and postoperative complications,but also reduce blood loss and transfusion,and improve the surgical field.