期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

对比剂使用后尿NGAL水平变化对肾脏损伤的探讨 被引量：1

下载PDF
导出
摘要 目的观察接受CT增强扫描检查的患者,在使用对比剂前后不同时间点尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)的水平变化,探讨尿NGAL在对比剂肾脏损伤的预测价值。方法选取接受CT增强扫描检查患者125例,检测其对比剂使用前后不同时间点尿NGAL及血肌酐(SCr)水平。结果推注对比剂后2、6、12、24、48及72 h SCr水平与对比剂使用前比较,差异无统计学意义(P>0.05);尿NGAL水平在术后2、6、12、24 h均显著升高,与对比剂使用前比较,差异有统计学意义(P<0.05)。结论对比剂使用后血肌酐(SCr)无明显升高患者,尿NGAL水平在使用对比剂2 h已有显著升高,提示尿NGAL对肾脏损伤早期的预测作用优于SCr。
作者 夏春燕 马彩霞 陈淑红
机构地区 宁夏银川市第一人民医院
出处 《宁夏医学杂志》 CAS 2015年第12期1135-1137,共3页 Ningxia Medical Journal
关键词 对比剂 中性粒细胞明胶酶相关脂质运载蛋白 肾脏损伤
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献9

  • 1Sirota JC, Walcher A,Faubel S, et al. Urine IL - 18, NGAL, IL - 8 and serum IL - 8 are biomarkers of acute kidney injury following liver transplantation[ J]. BMC Nephrology,2013,14( 1 ) :17.
  • 2Abassi Z, Sagi O, Armaly Z, et al. Neutrophil gelatinase - associated lipocalin(NGAL) : a novel biomarker for acute kidney injury [ J ]. Harefuah,2011,150(2) :111 - 116.
  • 3Clerico A, GaUi C, Fortunato A, et al. Neutrophil gelatinase - associ- ated lipocalin (NGAL)as biomarker of acute kidney injury:a review of the laboratory characteristics and clinical evidences [ J ]. Clinical Chemistry and Laboratory Medicine,2012,50 ( 9 ) : 1505 - 1517.
  • 4臧秀娟,安淑娴,郑峰,夏燕平,宋莹,于青.NGAL对大鼠肾脏缺血再灌注损伤作用机制的体内研究[J].实用医学杂志,2013,29(7):1060-1063. 被引量：9
  • 5Wi J,Ko YG,Kim JS,et al. Impact of contrast - induced acute kid- ney injury with transient or persistent renal dysfunction on long - term outcomes of patients with acute myocardial infarction undergo- ing percutaneous coronary intervention [ J ]. Heart, 2011,97 ( 21 ) : 1753 - 1757.
  • 6吉俊,丁小强,许迅辉,邹建洲,何建强,林贻梅,柏瑾,钱菊英.低渗非离子造影剂对冠状动脉介入诊疗术患者肾功能影响的前瞻性研究[J].中华肾脏病杂志,2006,22(7):388-392. 被引量：46
  • 7Feldkamp T, Kribben A. Contrast media induced nephropathy:defi- nition, incidence, outcome, pathophysiology, risk factors and preven- tion [ J ]. Minerva Medica,2008,99 (2) : 177 - 196.
  • 8Ling Wang,Zhaohui Ni,BEN He,et al. Urinary IL - 18 and NGAL as early predictive biomarkers in contrast - induced nephropathy af- ter coronary angiography [ J ]. Nephron Clinical Practice, 2008,108 (3) :c176-c181.
  • 9Bolignano D, Donato V, Coppolino G, et al. Neutrophil gelatinase - associated lipocalin (NGAL)as a marker of kidney damage [ J ]. A- merican Journal of Kidney Diseases,2008,52 ( 3 ) :595 - 605.

二级参考文献26

  • 1Best PJ,Lennon R,Ting HH,et al.The impact of renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary interventions.J Am Coll Cardiol,2002,39:1113-1119.
  • 2McCullough PA,Wolyn R,Rocher LL,et al.Acute renal failure after coronary intervention:incidence,risk factors,and relationship to mortality.Am J Med,1997,103:368-375.
  • 3Davidson C J,Laskey WK,Hermiller JB,et al.Randomized trial of contrast media utilization in high-risk PTCA:the COURT trial.Circulation,2000,101:2172-2177.
  • 4Cigarroa RG,Lange RA,Williams RH,et al.Dosing of contrast material to prevent contrast nephropathy in patients with renal disease.Am J Med,1989,86:649-652.
  • 5Solomon R.The role of osmolality in the incidence of contrast-induced nephropathy:a systematic review of angiographic contrast media in high risk patients.Kidney Int,2005,68:2256-2263.
  • 6Rihal CS,Textor SC,Grill DE,et al.Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention.Circulation,2002,105:2259-2264.
  • 7Rich MW,Crecelius CA.Incidence,risk factors,and clinical course of acute renal insufficiency after cardiac catheterization in patients 70 years of age or older.A prospective study.Arch Intern Med,1990,150:1237-1242.
  • 8Manske CL,Sprafka JM,Strony JT,et al.Contrast nephropathy in azotemic diabetic patients undergoing coronary angiography.Am J Med,1990,89:615-620.
  • 9Curhan GC.Prevention of contrast nephropathy.JAMA,2003,289:606-608.
  • 10Morcos SK,Thomsen HS,Webb JA.Contrast-media-induced nephrotoxicity:a consensus report.Contrast Media Safety Committee,European Society of Urogenital Radiology (ESUR).Eur Radiol,1999,9:1602-1613.

共引文献52

同被引文献15

引证文献1

二级引证文献2

宁夏医学杂志
2015年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部