654-2黄体酮碳酸氢钠联合治疗输尿管结石的可行性分析

An Analysis of the Feasibility to Treat Ureteral Calculi with 654-2 Progesterone in Combination with Sodium Bicarbonate

目的:探讨输尿管结石联合654-2(山莨菪碱)、黄体酮、碳酸氢钠治疗的效果。方法:抽取某院接诊的输尿管结石患者80例进行研究,所有患者均确诊,同时签署知情同意书愿意配合本次研究,随机均分为两组,各40例。对照组采取黄体酮治疗,研究组在对照组基础上联合654-2、碳酸氢钠治疗,观察记录两组患者临床效果、结石排出时间及随访半年复发率,并对比分析。结果:研究组总有效率为95.00%,对照组则为80.00%,研究组显著高于对照组(P<0.05);研究组结石排出时间为(5.45±1.27)d,对照组则为(7.94±2.16)d,研究组显著短于对照组(P<0.05);研究组随访半年复发率显著低于对照组(P<0.05)。结论:输尿管结石患者采取654-2、黄体酮、碳酸氢钠联合治疗可取得不错的效果,疗效明显,复发率低,有很高的临床价值,可行性高,值得借鉴。

Objective:To investigate the effect of 654-2scopolamine on in combination with progesterone and sodium bicarbonate on ureteral calculus.Method:Select 80 patients with ureteral calculi received in some hospital as the research object,all patients had been confirmed,signed informed consent and were willing to cooperate in this research,randomly divided them into 2groups,40 cases for each.The control group were treated with progesterone,on the basis of that in control group,the research group were added with 654-2,sodium bicarbonate,observe and record the clinical effect and lithecbole time and the relapse rate during the follow-up for half a year,and make analysis and comparison.Results:The total effective rate was 95.00%in research group,while that of the control group was 80.00%,the total effective rate of the research group was significantly higher than that of the control group(P<0.05);discharge time of calculus was 5.45+/-1.27 din research group,while that in control group was 7.94+/-2.16 d,the time in research group was significantly shorter than that in control group(P<0.05);The relapse rate during the follow-up for half a year in research group was significantly lower than that in control group(P>0.05).Conclusion:It would be effective to treat patients with ureteral calculi with 654-2,progesterone and sodium bicarbonate effect,its curative effect is significant,and the recurrence rate would be low,it is of great clinical value,it is feasible and worthy of reference.