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免疫学在过敏性紫癜肾炎发病机制中的作用 被引量：2

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摘要 过敏性紫癜（HSP）是2-8岁儿童常见的无菌性小血管炎疾病,多易侵犯肾脏,称为过敏性紫癜性肾炎（HSPN）。过敏性紫癜由初期发病发展为紫癜性肾炎,通常在病程的4-6周发生。虽然过敏性紫癜性肾炎发病机制未完全阐述清楚,但一些研究表明免疫因素与其存在一定关联。1抗体介导的免疫复合物在过敏性紫癜性肾炎发病机制中的作用1.1 IgA血液循环中IgA来源于B细胞克隆活化分泌产生,有IgA1和IgA2两个亚型,
作者 于少飞 冯万禹 梁妍琰
机构地区 内蒙古自治区人民医院儿科
出处 《内蒙古医学杂志》 2015年第8期957-958,共2页 Inner Mongolia Medical Journal
关键词 免疫 胰岛素样生长因子-1 紫癜性肾炎
分类号 R692.3 [医药卫生—泌尿科学]
  • 相关文献

参考文献18

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  • 4Suzuki H,Moldoveanu Z,Wyatt R,et al.Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy:role of mucosal immune system[J].Adv Otorhinolaryngol,2011;72:60-63.
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二级参考文献47

  • 1张昱,陶世文,杨魁兰.儿童过敏性紫癜287例临床分析[J].新疆医科大学学报,2004,27(3):270-272. 被引量：31
  • 2陈谱,何韶衡,陈穗.过敏性紫癜患儿血浆白细胞介素-17、-10、-4及干扰素-γ水平的临床意义[J].实用儿科临床杂志,2004,19(11):969-970. 被引量：12
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共引文献48

同被引文献28

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二级引证文献8

内蒙古医学杂志
2015年 第8期

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