注射外源性生长因子致面部肿物的临床治疗

Clinical efficacy of facial masses caused by exogenous growth factor injections

目的 探讨面部注射外源性生长因子后产生肿物的可能原因和处理方案.方法 对17例面部注射外源性生长因子并产生面部肿物的患者进行回顾性分析,17例中有15例位于颏部,行颏部肿物切除及颏下颈阔肌间脂肪筋膜瓣修复术,另外2例位于面颊部,单纯行面颊部肿物切除,术后抗瘢痕治疗,6个月术后调查满意度.结果 17例患者中只有3例可明确是碱性成纤维细胞生长因子.另外14例患者的注射物不知具体生长因子名称.17例切口均愈合良好,术后6个月行彩色多普勒超声检查,未发现肿物残留或者复发.17例中只有1例两侧不对称,需要进一步治疗,16例对修复后面部外观满意.结论 注射外源性生长因子后致面部肿物,可及时行切除术,如创面较大,术中可行局部脂肪筋膜瓣修复,结合防治瘢痕,可获得较高的满意度.

Objective To explore the reasons and the best treatment options of facial mass complicated after exogenous growth factor injections.Methods 17 cases of postoperative complications caused by exogenous growth factor injections were retrospectively analyzed.15 patients with chin masses received mass resection and repairment with submental fat and fascial flap.Facial masses of the other 2 patients were located in cheek.Simple cheek mass resection was usually useful.All the patients had scar treatment.The postoperative satisfactory survey was investigated after 6 months.Results The incisions of 17 patients were healed well.An analysis through color Doppler ultrasound examination showed no residual or recurrent mass within half a year follow-up.One of the 17 patients had facial asymmetry and needed further treatment.Others were satisfied with the facial appearance of treatment.Conclusions The masses resulted from injection of exogenous growth factor should be cut off timely and reasonable reconstruction through fat and fascial flap and scar treatment are helpful to restore the original appearance of patients.