比索洛尔联合辛伐他汀治疗老年人不稳定型心绞痛的效果观察

Observation of the effect of bisoprolol combined with simvastatin in the treatment of elderly patients with unstable angina

目的：观察索洛尔联合辛伐他汀治疗老年人不稳定型心绞痛的临床效果。方法60例老年不稳定型心绞痛患者按照数字表法随机分为对照组和研究组，对照组患者使用辛伐他汀进行治疗，对研究组患者使用比索洛尔联合辛伐他汀进行治疗。比较两组的临床治疗效果及不良反应发生情况。结果研究组心绞痛治疗总有效率和心电图有效率（86．67％和80．00％）明显高于对照组（76．67％和46．67％）（χ2＝4．02、7．18，均 P ＜0．05）；研究组不良反应总发生率（26．67％）与对照组（30．00％）差异无统计学意义（χ2＝0．08， P ＞0．05）。结论比索洛尔联合辛伐他汀治疗老年不稳定型心绞痛的效果较好，不良反应小，值得临床推广使用。

Objective To observe the clinical effect of bisoprolol combined with simvastatin in the treatment of elderly patients with unstable angina pectoris.Methods 60 elderly patients with unstable angina pectoris were randomly divided into control group and study group according to the digital table method.The patients in the control group were treated with simvastatin,and the patients in the study group were treated with bisoprolol and simvastatin.The clinical therapeutic effect and adverse reactions of the two groups were compared.Results The total effective rate and the rate of ECG （86.67% and 80%）in the study group were significantly higher than those of the control group （76.67% and 46.67%）（χ2 =4.02,7.1 8,all P 〈0.05 ）.The total incidence rate of adverse reactions （26.67%）in the study group had no significant difference compared with the control group （χ2 =0.08,P 〉0.05）. Conclusion Bisoprolol combined with simvastatin had better clinical effect and small adverse reactions in the treat-ment of elderly patients with unstable angina.It was worthy of clinical use.