CHADS2评分在甲状腺机能亢进合并房颤的抗栓治疗中的应用

Application of CHADS2 score in the treatment of thrombus of patients with hyperthyroidism and atrial fibrillation

目的观察CHADS2评分在甲状腺机能亢进合并房颤的抗栓治疗中的应用效果。方法抽取入医院治疗的甲状腺机能亢进合并房颤患者84例作为研究对象,采用掷骰子的方式将患者随机分为两组,观察组应用CHADS2评分观察并进行抗凝治疗,对照组进行常规治疗,比较二组栓塞事件发生几率。结果显示观察组血栓栓塞事件发生率2.38%明显低于对照组7.14%,差异具有统计学意义(P<0.05)。观察组患者甲亢症状改善时间、住院费用、住院时间分别为(6.17±2.03)d、(4.17±2.03)千元、(6.17±2.03)d均较对照组低,差异具有统计学意义(P<0.05)。结论应用CHADS2评分进行抗凝组与不应用评分组且不进行抗凝组血栓栓塞事件发生率明显下降,CHADS2评分可应用于甲亢合并房颤的抗栓治疗。

Objective To observe the application effect of CHADS2 score in the treatment of thrombus of patients with hyperthyroidism combined with atrial fibrillation. Methods 84 patients with hyperthyroidism and atrial fibrillation were randomly divided into two groups. The observation group was treated with anticoagulant therapy and observed the efficacy through CHADS2 score. The control group was treated with conventional therapy. The incidence of embolization events of the two groups was compared. Results The results showed that the incidence of thrombosis in the observation group（ 2. 38%） was significantly lower than that in the control group（ 7. 14%）,the difference was statistically significant（ P〈0. 05）. The improvement time,hospitalization expenses,hospitalization time of the observation group（ 6. 17 ± 2. 03 d,4. 17 ± 2. 03 thousand Yuan and 6. 17 ±2. 03d） were lower than those of the control group,the differences were statistically significant（ P〈0. 05）.Conclusions CHADS2 score could be used in the treatment of hyperthyroidism combined with atrial fibrillation.