手-口综合征临床分析

Cheiro-oral syndrome

回顾分析11例手-口综合征患者临床和影像学特点,结果显示:均为单侧病变,急性腔隙性梗死10例、脑出血1例;以丘脑缺血性卒中(5例)常见,其次分别为顶叶(3例)和脑干(3例),其中3例治疗过程中病情加重。随访3个月,治疗后2例遗留单侧口周和指尖麻木感、1例病情进展遗留偏身感觉障碍。延髓至顶叶神经传导功能受损可引起手-口综合征,尽管多数患者预后良好,但个别患者仍有病情进展风险。

The clinical and imaging features of 11 cheiro- oral syndrome（COS） cases wereretrospectively analyzed. All patients were unilaterally involved, including 10 cases of acute lacunarcerebral infarction, and one case of cerebral hemorrhage. Thalamic ischemic stroke（5 cases） was mostcommon, and secondly were parietal lobe infarction（3 cases） and brainstem infarction（3 cases）. Three of11 cases developed progressive stroke during treatment. All patients were followed up for 3 months afterdischarge, 2 cases still presented ipsilateral fingertips and perioral numbness, one progressive case left hemi-dysesthesia. Damage of nerve conduction from medulla oblongata to parietal lobe can induce COS.Although the prognosis of COS is good, progressive risk can be seen in some cases.