ABVS和HHUS鉴别诊断良恶性乳腺肿瘤的meta分析

Diagnostic accuracy of ABVS versus HHUS for benign and malignant lesions in breasts :a meta-analysis

目的：运用Meta分析评价自动乳腺全容积成像系统（automated breast volume scanning,ABVS）与手持探头超声（hand-held ultrasound,HHUS）对乳腺良、恶性肿瘤的诊断价值。方法 ：采用计算机自动配合手工检索COCHRANE、WEB OF SCIENCE、PUBMED、EMBASE、中文科技期刊全文数据库、中国生物医学文献数据库、中国知网（CNKI）、万方数字化期刊全文数据库（检索时间：建库至2015年3月7日）,搜集并筛选出HHUS与ABVS鉴别诊断女性良恶性乳腺肿瘤的文献,应用STATA12.0软件对入选文献的试验数据进行分析。结果 ：17篇文献符合纳入标准。ABVS和HHUS合并诊断比值比分别为95.21（53.85-168.36）、28.88（16.15-51.66）,合并特异度分别为0.90（0.86-0.93）、0.84（0.78-0.89）,合并敏感度分别为0.91（0.88-0.93）、0.84（0.79-0.88）。结论 ：ABVS在乳腺良、恶性肿瘤鉴别诊断方面较HHUS具有更高的临床价值。

Objective：To assess the diagnostic value of automated breast volume scanning（ABVS） versus hand-held ultrasound（HHUS） in benign and malignant breast tumor by meta-analysis. Methods： The Cochrane Library,Web of Science,the Pub Med,EMBASE,VIP,CBM,CNKI and Wanfang databases（From date of creating database to 2015 / 03 / 07） were searched for studies on the diagnosis of breast cancer with ABVS and HHUS according to inclusion criteria,and then STATA12.0 software was performed to analyze the selected documents. Results： A total of 17 studies were included after screening. The pooled diagnostic odds ratio,specificity and sensitivity of ABVS and HHUS were 95.21（53.85-168.36）and 28.88（16.15-51.66）, 0.90（0.86-0.93） and 0.84（0.78-0.89）, 0.91（0.88-0.93）and 0.84（0.79-0.88）, respectively. Conclusion：The results of meta-analysis suggest that ABVS has higher value than HHUS in the diagnosis of benign and malignant breast tumor.