从肝论治类风湿关节炎探讨

Study on Treating Rheumatoid Arthritis Through Regulation of Liver

类风湿关节炎是一种以对称性多关节炎为主要临床表现的自身免疫性疾病,早期类风湿关节炎的病理特点为滑膜炎,炎症可以引起破骨细胞的过度活化,从而导致关节骨破坏,控制滑膜炎症是目前治疗类风湿关节炎的主要方法。滑膜属中医"筋"的范畴,肝主筋,肝在筋的生理和病理过程中发挥重要作用,肝脏气血失调是类风湿关节炎诸多临床表现的内在病机。肝与类风湿关节炎在病位和病机方面存在广泛联系,这对类风湿关节炎的防治具有重要指导作用。

Rheumatoid arthritis（RA） is a kind of autoimmune disease,and its main clinical manifestation is symmetric polyarthriti.Synovitis is the main pathological characteristics of early RA,which can cause excessive activation of osteocytes,leading to joint bone destruction.Treating synovitis is the currant major method for the treatment of RA.Traditional Chinese Medicine believed that synovium belongs to ＂tendon＂,and since liver charges tendon,liver plays an important role in the physiological and pathological processes of tendon.Besides,liver qi and blood disorder is the pathogenesis of many clinical manifestations of RA.Therefore,it is fair to say that there are a wide range of connections between liver and rheumatoid arthritis in terms of disease location and pathogenesis,which will be useful for the prevention of RA.