中西医结合五联疗法治疗慢性乙型病毒性肝炎临床分析

Clinical Analysis on the Therapy of Integrated Medicine combined with Immovable Therapy in the Treatment of Chronic Hepatitis B Viral

目的观察分析五联疗法的临床疗效,找到慢性乙型病毒肝炎的最理想的治疗药物与手段。方法主要将病患划分成治疗组与对照组这两个组别,其中针对对照组患者实施五联疗法,面向对照组患者肌肉注射α-干扰素。对比观察治疗前后的体征变化、症状表现、肝功能、肝纤维化参数的变动、病毒复制参数。结果治疗组的显效率达到70.12%、总有效率达到97.23%,大大超出对照组42.15%、83.35%;HBV DNA阴转率达到57.31%、HBe Ag阴转率达到54.40%,明显高于对照组43.35%、38.26%;肝纤维化参数显著降低,明显区别于对照组。结论中西医结合无联疗法可显著改进慢性乙型肝炎患者的体态特征、症状表现与抗病毒等,其临床疗效大大优于干扰素。

Objective To observe the clinical curative effect of immovable, and to find the optimal therapy and means for chronic hepatitis b virus. Methods Patients were divided into treatment group and control group. The control group used immovable therapy. The treatment group received intramuscular alpha interferon. Signs and symptoms, liver function, liver fibrosis parameters change and viral replication parameters before and after treatment were observed and compared. Results The complete relief rate and the effective rate of the treatment group was 70.12% and 97.23%, respectively, which was higher that 42.15% and 83.35% of the control group, respectively. The negative conversion rate of HBV DNA and HBeAg of the treatment group was 57.31% and 54.40%, respectively, which was significantly higher than 43.35% and 38.26% of the control group, respectively. Liver fibrosis parameters were significantly reduced, which was significantly different from the control group. Conclusion Therapy of integrated medicine combined with immovable therapy can significantly improve the posture characteristics and manifestation of patients with chronic hepatitis b viral, and its clinical curative effect was significantly superior to interferon.