非呼吸道感染金黄色葡萄球菌临床分布及耐药性研究

Study on the clinical distribution and drug resistance of Staphylococcus aureus from non respiratory tract infection

目的研究非呼吸道感染的金黄色葡萄球菌临床分布和耐药特点,为临床合理有效地控制感染提供依据。方法通过细菌分离鉴定技术和药敏试验方法,对某医院临床送检非呼吸道标本检验结果进行调查与分析。结果从该医院临床送检的非呼吸道标本中共检出金黄色葡萄球菌291株,其中耐甲氧西林金黄色葡萄球菌(MRSA)86株,占29.55%。金黄色葡萄球菌主要分离自分泌物和脓液,但MRSA检出率最高的标本是尿液和穿刺液。MRSA菌株检出最高的科室是重症监护病房(ICU),其次是脑外科和泌尿烧伤科。临床分离的金黄色葡萄球菌对青霉素、红霉素及克林霉素的耐药率较高,MRSA对青霉素全部耐药。结论引起非呼吸道感染的金黄色葡萄球菌,对多种抗菌药物耐药率较高,ICU成为控制金黄色葡萄球菌感染的重点部位。

Objective To study the clinical distribution and the drug resistance characteristics of Staphylococcus aureus,provide the basis for the infection control. Methods We investigate and analyze the results of non respiratory tract specimens in a hospital by the technologies of bacterial isolation and identification and drug sensitive test. Results A total of291 strains of S. aureus were isolated,including 86 strains of MRSA,accounting for 29. 55%. S. aureus were mainly separated from the secretions and pus,but the highest detection rate of the MRSA strains were urine specimen and puncture fluid. The department of highest examination rate of MRSA was Intensive care unit（ ICU）,followed by the brain surgery and urinary acute. S. aureus had high resistance to penicillin,erythromycin and clindamycin,and all MRSA were resistant to penicillin. Conclusion The Staphylococcus aureus causing of the infection of non respiratory tract have a high resistance to many kinds of antimicrobial,and ICU is key parts of Staphylococcus aureus infection control.