女性下生殖道假丝酵母菌感染患者解脲脲原体与沙眼衣原体混合感染情况研究

Mixed infection of Ureaplasma urealyticum and Chlamydia trachomatis in female lower genital tract Candida infection

目的:探究并分析女性下生殖道假丝酵母菌(VVC)感染患者解脲脲原体(UU)与沙眼衣原体(CT)混合感染情况。方法:选取我院自2012年12月至2014年12月收治的下生殖道假丝酵母菌感染患者103例作为病例组,并征集于我院体检的健康女性250例,作为对照组。将病例组分为单纯组、重度组以及复发组。对所有患者进行UU、CT阳性率检查,并分别记录下UU阳性率、CT阳性率以及UU混合CT阳性率。结果:单纯组、重度组、复发组患者之间UU阳性、CT阳性、UU混合CT阳性率无明显差异(P>0.05),无统计学意义。对照组患者UU阳性为8.4%,病例组患者UU阳性为57.2%,明显高于对照组患者(χ2(病,对)=17.134,P=0.002),具有统计学意义。单纯组、重度组、复发组患者均明显高于对照组患者UU阳性率(χ2(单,对)=8.932,P=0.004;χ2(重,对)=8.362,P=0.005;χ2(复,对)=4.567,P=0.034),具有统计学意义。结论:患有VVC的女性常伴有生殖道UU感染,两者有着密切的联系,但VVC的严重程度与女性生殖道UU感染无明显联系,而CT感染与VVC的发生无明显相关性,尚需进一步研究。

Objectives： To explore and analyze the mixed infection of Ureaplasma urealyticum （UU） and Chlainydia trachomatis （CT） in female reproductive tract Candida （VVC） infection. Methods： 103 patients with VVC infection in our hospital from December 2012 to December 2014 were selected as the case group and 250 healthy women in our hospital for physical examination were chosen as the control group. Patients in the case group were divided into simple group, severe group, and relapse group. All patients received UU, CT examination and the positive rate of UU, CT and mixed CT and UU were recorded. Results： No significant differences were found be- tween simple group, severe group, and relapse group in UU -positive, CT- positive and mixed positive rate （P 〉 0. 05）. The UU -positive rate in the control group and case group was 8.4% and 57.2% respectively, with statis- tically significant difference （ X2（case,control） = 17. 134, P = 0. 002）. The UU - positive rate in the simple group, se- vere group and relapse group were significantly higher than the control group, with statistically significant difference X2 （ simple,control） = 8.932, P= 0.004;X（ ~） = 8.362, P= 0.005;X2（relapue,control） = 4.567, P= 0.034）. Conclusions： Female with VVC infection is often accompanied by UU reproductive tract infections, but the severity of VVC and female reproductive tract infection UU is not significantly related, and CT infection is not significantly related with the incidence of VVC, but further research is needed.